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/lp/karger/final-height-in-children-with-growth-hormone-deficiency-M5bxKx8Akw
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- Publisher
- Karger
- Copyright
- © 1995 S. Karger AG, Basel
- ISSN
- 1663-2818
- eISSN
- 1663-2826
- DOI
- 10.1159/000184256
- Publisher site
- See Article on Publisher Site
Abstract
Forty-six patients (28 boys, 18 girls) were treated with growth hormone (GH) for short stature. Twenty-eight patients had total growth hormone deficiency (GHD), 12 partial GHD and 6 patients had short stature without GHD. Brain tumours were the cause of GHD in 8 patients and multiple pituitary hormone deficiency was present in 9 children. All patients received GH with subcutaneous injections only, 6-7 times/week. Mean final height for all patients was -1.11 SDS and was similar in boys ( 1.09 SDS) and girls (-1.13 SDS). Target height SDS was -0.80 SDS in 42 patients, comparing favourably with a final height SDS of-1.05. Similar results were obtained in all patient sub-groups. Height velocity during the last year of therapy was between 2.1 and 9.9 cm/ year in 34 patients and below 2 cm in 12 patients. As further growth is to be expected, target height will probably be reached by most patients.
Journal
Hormone Research in Paediatrics – Karger
Published: Jan 1, 1995
Keywords: Complete growth hormone deficiency; Partial growth hormone deficiency; Short stature without growth hormone deficiency; Subcutaneous injection of growth hormone; Final height; Target height