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Case Reports Epithelial Myoepithelial Carcinoma of the Parotid Gland with Malignant Ductal and Myoepithelial Components Arising in a Pleomorphic Adenoma A Case Report with Cytologic, Histologic and Immunohistochemical Correlation Yahya Daneshbod, M.D., Shahrzad Negahban, M.D., Bijan Khademi, M.D., and Khosrow Daneshbod, M.D., F.C.A.P. Background ically reported as “pleomorphic adenoma, with focal inva- To describe the cytologic, histologic and immunohistochemi- sion of one resected margin.” Four months later the tumor cal findings of a case of epithelial myoepithelial carcinoma recurred, and FNAB showed almost the same cytologic fea- (EMC) arising from a pleomorphic adenoma (PA) of the tures as did the previous aspirate. Due to early recurrence, parotid with both malignant epithelial and myoepithelial previous histologic sections were reviewed, and typical areas components. of a biphasic pattern of EMC with atypicality and mitosis of both components was found. Case The final diagnosis was EMC We stress the importance of A 29-year-old female present- ex PA. ed with a 1.5 × 1.5-cm, palpa- distinguishing EMC from PA and Conclusion ble mass of the left parotid of consideration of the coexistence of 7–8 months’ duration with Although previous reports recent enlargement and pain. mention the difficulties in di- both tumors. Fine needle
Acta Cytologica – Karger
Published: Jan 1, 2011
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