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/lp/karger/drug-induced-granulocytopenia-with-natural-killer-lymphocytosis-after-jzvnMeTBEH
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- Publisher
- Karger
- Copyright
- © 1990 S. Karger AG, Basel
- ISSN
- 0001-5792
- eISSN
- 1421-9662
- DOI
- 10.1159/000205177
- Publisher site
- See Article on Publisher Site
Abstract
Following renal transplantation, a patient developed life-threatening granulocytopenia secondary to a specific combination of drugs which are commonly utilized in this setting. Coincident with the depression of granulocytes, an expansion of natural killer cells was seen, which may have been a consequence of immunosuppressive therapy required for allograft retention. Infection with cytomegalovirus may have contributed to both phenomena.
Journal
Acta Haematologica – Karger
Published: Jan 1, 1990
Keywords: Cytomegalovirus; Granulocytopenia; Natural killer cell; Transplantation, renal