Get 20M+ Full-Text Papers For Less Than $1.50/day. Start a 14-Day Trial for You or Your Team.

Learn More →

Correlation in Hemodialysis Patients and Renal Allograft Recipients between Percent T Lymphocytes in Peripheral Blood and in vitro Lymphocyte Responses to Nonspecific Mitogenic Agents

Correlation in Hemodialysis Patients and Renal Allograft Recipients between Percent T Lymphocytes... Both hemodialysis and renal allograft recipients have a significantly reduced number of total T lymphocytes per microliter of blood. Simultaneous in vitro lymphocyte responsiveness to phytohemagglutinin (PHA) and pokeweed mitogen (PWM) revealed in the normal subjects, a positive correlation (r = +0.427) between percent T lymphocytes and PHA and a negative correlation (r = -0.525) between percent T lymphocytes and PWM. Such trends were not observed in the hemodialysis patients and transplant recipients. Thus, the enumeration of lymphocytes as T cells appears to provide no clear indication of their functional capacity to respond to mitogenic stimulation in these two categories of patients. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Acta Haematologica Karger

Correlation in Hemodialysis Patients and Renal Allograft Recipients between Percent T Lymphocytes in Peripheral Blood and in vitro Lymphocyte Responses to Nonspecific Mitogenic Agents

Sengar, D.P.S.; Rashid, A.; Harris, J.E.
Acta Haematologica , Volume 54 (3): 6 – Jan 1, 1975
Download PDF
6 pages

Loading next page...
 
/lp/karger/correlation-in-hemodialysis-patients-and-renal-allograft-recipients-VVokP30q3y

References

References for this paper are not available at this time. We will be adding them shortly, thank you for your patience.

Publisher
Karger
Copyright
© 1975 S. Karger AG, Basel
ISSN
0001-5792
eISSN
1421-9662
DOI
10.1159/000208067
Publisher site
See Article on Publisher Site

Abstract

Both hemodialysis and renal allograft recipients have a significantly reduced number of total T lymphocytes per microliter of blood. Simultaneous in vitro lymphocyte responsiveness to phytohemagglutinin (PHA) and pokeweed mitogen (PWM) revealed in the normal subjects, a positive correlation (r = +0.427) between percent T lymphocytes and PHA and a negative correlation (r = -0.525) between percent T lymphocytes and PWM. Such trends were not observed in the hemodialysis patients and transplant recipients. Thus, the enumeration of lymphocytes as T cells appears to provide no clear indication of their functional capacity to respond to mitogenic stimulation in these two categories of patients.

Journal

Acta Haematologica – Karger

Published: Jan 1, 1975

Keywords: Cellular immunity; Hemodialysis; Lymphocyte stimulation; Renal transplantation; T Lymphocytes

There are no references for this article.