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<h2>Introduction</h2> Osteosarcomas rarely occur in the hand 12 . This primary neoplasm of bone may be classified, on the basis of its origin, as central, juxtacortical, or extraskeletal. Extraskeletal osteosarcomas are extremely rare and, although their true prevalence is unknown, it has been estimated that they account for approximately one in twenty-five (twenty-six of 650 1 ) reported cases of primary osteosarcoma of bone. Extraskeletal osteosarcomas are located in the soft tissues without skeletal or periosteal attachment, and they have a uniform sarcomatous pattern and a matrix composed of osteoid or cartilage, or both. In contradistinction to primary osteosarcoma of bone, this variant typically develops after the fourth decade of life 1 and the prognosis is uniformly poor 1 , 2 , 4 , 5 , 8 , 9 , 11 , 14 , 15 . In the present report, we document the clinical and pathological findings in a patient who had an extraskeletal osteosarcoma arising from the thenar muscles of the hand. <h2>Case Report</h2> A sixty-three-year-old man was referred to the Raymond M. Curtis Hand Center because of a rapidly enlarging, painless mass in the left hand. The patient had noticed the mass five months earlier, after
Journal of Bone and Joint Surgery – Wolters Kluwer Health
Published: May 1, 1998
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