Get 20M+ Full-Text Papers For Less Than $1.50/day. Start a 14-Day Trial for You or Your Team.

Learn More →

Efficacy of Surgical Preparation Solutions in Foot and Ankle Surgery

Efficacy of Surgical Preparation Solutions in Foot and Ankle Surgery To The Editor: I am writing to point out two limitations not mentioned in the study presented in your article, "Efficacy of Surgical Preparation Solutions in Foot and Ankle Surgery" (2005;87: 980-5 ), by Ostrander et al. No neutralizing ingredient(s) (neutralizer) was used in the sampling method, either on the swab or in the transport or culture media. American Society for Testing and Materials (ASTM) method E1054-02 recommends adding appropriate neutralizers to the solution used for sampling skin. A neutralizer inactivates an antimicrobial at sampling so that there is no further kill in the test tube while the sample is waiting to be diluted and plated for quantification. If a neutralizer is not present, the antimicrobial will continue to kill bacteria in vitro, resulting in an erroneous higher kill rate. The lack of a neutralizer would inflate the efficacy of the water-soluble preparations (Techni-Care and ChloraPrep) tested. The second limitation is the sampling method. 3M DuraPrep Surgical Solution forms a water-insoluble film when it dries. Sampling solution with or without neutralizer will not dissolve the DuraPrep film to allow sampling of the skin beneath. Since the other antimicrobials are water-soluble, the sampling method is not consistent between products. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Journal of Bone and Joint Surgery Wolters Kluwer Health

Efficacy of Surgical Preparation Solutions in Foot and Ankle Surgery

Journal of Bone and Joint Surgery , Volume 88 (5): 1160 – May 1, 2006
7 pages

Loading next page...
 
/lp/jb-js/efficacy-of-surgical-preparation-solutions-in-foot-and-ankle-surgery-TZxcfxGLqF

References

References for this paper are not available at this time. We will be adding them shortly, thank you for your patience.

Publisher
Wolters Kluwer Health
Copyright
Copyright © 2006 by The Journal of Bone and Joint Surgery, Inc.
ISSN
0021-9355
Publisher site
See Article on Publisher Site

Abstract

To The Editor: I am writing to point out two limitations not mentioned in the study presented in your article, "Efficacy of Surgical Preparation Solutions in Foot and Ankle Surgery" (2005;87: 980-5 ), by Ostrander et al. No neutralizing ingredient(s) (neutralizer) was used in the sampling method, either on the swab or in the transport or culture media. American Society for Testing and Materials (ASTM) method E1054-02 recommends adding appropriate neutralizers to the solution used for sampling skin. A neutralizer inactivates an antimicrobial at sampling so that there is no further kill in the test tube while the sample is waiting to be diluted and plated for quantification. If a neutralizer is not present, the antimicrobial will continue to kill bacteria in vitro, resulting in an erroneous higher kill rate. The lack of a neutralizer would inflate the efficacy of the water-soluble preparations (Techni-Care and ChloraPrep) tested. The second limitation is the sampling method. 3M DuraPrep Surgical Solution forms a water-insoluble film when it dries. Sampling solution with or without neutralizer will not dissolve the DuraPrep film to allow sampling of the skin beneath. Since the other antimicrobials are water-soluble, the sampling method is not consistent between products.

Journal

Journal of Bone and Joint SurgeryWolters Kluwer Health

Published: May 1, 2006

There are no references for this article.