Key PointsQuestionCan a negative high-sensitivity troponin assay at 0 and 3 hours following emergency department presentation identify patients at less than 1% risk of 30-day adverse cardiac events? FindingsIn this multicenter evaluation, a single high-sensitivity troponin level less than 6 ng/L ruled out myocardial infarction, while serial levels at 19 ng/L or less identified patients at less than 1% risk of 30-day adverse cardiac events. MeaningIdentifying a low-risk cohort may permit early emergency department discharge and avoid unnecessary hospitalization.
JAMA Cardiology – American Medical Association
Published: Feb 13, 2018
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