Effect of Bag-Mask Ventilation vs Endotracheal Intubation During Cardiopulmonary Resuscitation on Neurological Outcome After Out-of-Hospital Cardiorespiratory Arrest

Effect of Bag-Mask Ventilation vs Endotracheal Intubation During Cardiopulmonary Resuscitation on... Key PointsQuestionIs bag-mask ventilation noninferior to endotracheal intubation for initial airway management during advanced resuscitation of patients with out-of-hospital cardiac arrest? FindingsIn this randomized clinical trial that included 2043 patients, favorable neurological function at 28 days was present in 4.3% in the bag-mask group vs 4.2% in the endotracheal intubation group, a difference that did not meet the noninferiority margin of 1%. MeaningThe study findings are inconclusive for noninferiority; further research would be necessary to assess equivalence or superiority. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png JAMA American Medical Association

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Publisher
American Medical Association
Copyright
Copyright 2018 American Medical Association. All Rights Reserved.
ISSN
0098-7484
eISSN
1538-3598
D.O.I.
10.1001/jama.2018.0156
Publisher site
See Article on Publisher Site

Abstract

Key PointsQuestionIs bag-mask ventilation noninferior to endotracheal intubation for initial airway management during advanced resuscitation of patients with out-of-hospital cardiac arrest? FindingsIn this randomized clinical trial that included 2043 patients, favorable neurological function at 28 days was present in 4.3% in the bag-mask group vs 4.2% in the endotracheal intubation group, a difference that did not meet the noninferiority margin of 1%. MeaningThe study findings are inconclusive for noninferiority; further research would be necessary to assess equivalence or superiority.

Journal

JAMAAmerican Medical Association

Published: Feb 27, 2018

References

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