Drug Interactions With Non–Vitamin K Oral Anticoagulants

Drug Interactions With Non–Vitamin K Oral Anticoagulants Letters Accepted for Publication: December 1, 2017. From 2011 to 2014, statistically significant reductions in RBC transfusions were seen among all sexes, race/ethnicities, Corresponding Author: Aaron Tobian, MD, PhD, Department of Pathology, Johns Hopkins University, Carnegie 437, 600 N Wolfe St, Baltimore, MD 21287 patient risk severities, payer types, and admission types (atobian1@jhmi.edu). (Table). No statistically significant reductions in RBC transfu- Author Contributions: Drs Goel and Tobian had full access to all of the data in sions were seen in children (aged <18 years) or private the study and take responsibility for the integrity of the data and the accuracy investor–owned hospitals. Significant interactions were of the data analysis. Concept and design: Goel, Chappidi, Patel, Ness, Frank, Tobian. observed for time and all covariates (P for interaction < .05). Acquisition, analysis, or interpretation of data: Goel, Chappidi, Patel, Cushing, A significantly greater decrease in RBC transfusions was seen Frank, Tobian. for elective admissions (aRR, 0.74 [95% CI, 0.67-0.80]) com- Drafting of the manuscript: Goel, Chappidi, Patel, Tobian. pared with nonelective admissions (aRR, 0.86 [95% CI, 0.81- Critical revision of the manuscript for important intellectual content: Goel, Chappidi, Patel, Ness, Cushing, Frank. 0.91]; P for interaction < .001). Statistical analysis: http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png JAMA American Medical Association

Drug Interactions With Non–Vitamin K Oral Anticoagulants

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Publisher
American Medical Association
Copyright
Copyright 2018 American Medical Association. All Rights Reserved.
ISSN
0098-7484
eISSN
1538-3598
D.O.I.
10.1001/jama.2017.20842
Publisher site
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Abstract

Letters Accepted for Publication: December 1, 2017. From 2011 to 2014, statistically significant reductions in RBC transfusions were seen among all sexes, race/ethnicities, Corresponding Author: Aaron Tobian, MD, PhD, Department of Pathology, Johns Hopkins University, Carnegie 437, 600 N Wolfe St, Baltimore, MD 21287 patient risk severities, payer types, and admission types (atobian1@jhmi.edu). (Table). No statistically significant reductions in RBC transfu- Author Contributions: Drs Goel and Tobian had full access to all of the data in sions were seen in children (aged <18 years) or private the study and take responsibility for the integrity of the data and the accuracy investor–owned hospitals. Significant interactions were of the data analysis. Concept and design: Goel, Chappidi, Patel, Ness, Frank, Tobian. observed for time and all covariates (P for interaction < .05). Acquisition, analysis, or interpretation of data: Goel, Chappidi, Patel, Cushing, A significantly greater decrease in RBC transfusions was seen Frank, Tobian. for elective admissions (aRR, 0.74 [95% CI, 0.67-0.80]) com- Drafting of the manuscript: Goel, Chappidi, Patel, Tobian. pared with nonelective admissions (aRR, 0.86 [95% CI, 0.81- Critical revision of the manuscript for important intellectual content: Goel, Chappidi, Patel, Ness, Cushing, Frank. 0.91]; P for interaction < .001). Statistical analysis:

Journal

JAMAAmerican Medical Association

Published: Feb 27, 2018

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