Key PointsQuestionWhat is the incremental prognostic value of urinary albumin excretion for cardiovascular risk assessment in patients with diabetes with and without the incorporation of cardiac biomarkers? FindingsIn this secondary analysis of a randomized clinical trial population of 15 760 patients with type 2 diabetes and high cardiovascular risk, there was a stepwise increased risk of cardiovascular events according to baseline urinary albumin to creatinine ratio. The association with increased risk was present even at low-level elevations of urinary albumin to creatinine ratio, which are otherwise considered normal, although this relationship was attenuated when adjusted for cardiac biomarkers. MeaningLow levels of albuminuria improve risk stratification for future cardiovascular risk in patients with type 2 diabetes; urinary albumin to creatinine ratio provides minimal incremental prognostic utility beyond cardiac biomarkers.
JAMA Cardiology – American Medical Association
Published: Feb 6, 2018
Read as many articles as you need. Full articles with original layout, charts and figures. Read online, from anywhere.
Keep up with your field with Personalized Recommendations and Follow Journals to get automatic updates.
It’s easy to organize your research with our built-in tools.
Read from thousands of the leading scholarly journals from SpringerNature, Elsevier, Wiley-Blackwell, Oxford University Press and more.
All the latest content is available, no embargo periods.
“Hi guys, I cannot tell you how much I love this resource. Incredible. I really believe you've hit the nail on the head with this site in regards to solving the research-purchase issue.”Daniel C.
“Whoa! It’s like Spotify but for academic articles.”@Phil_Robichaud
“I must say, @deepdyve is a fabulous solution to the independent researcher's problem of #access to #information.”@deepthiw
“My last article couldn't be possible without the platform @deepdyve that makes journal papers cheaper.”@JoseServera