Association of Varicose Veins With Incident Venous Thromboembolism and Peripheral Artery Disease

Association of Varicose Veins With Incident Venous Thromboembolism and Peripheral Artery Disease Key PointsQuestionAre varicose veins associated with an increased risk of developing deep venous thrombosis (DVT), pulmonary embolism (PE), or peripheral artery disease (PAD)? FindingsIn this retrospective cohort study from Taiwan that included 425 968 adults, the presence of varicose veins was associated with a significantly increased risk of incident DVT (hazard ratio [HR], 5.30), PE (HR, 1.73), and PAD (HR, 1.72). MeaningThis study found a significant association between varicose veins and DVT, and less clear potential associations with PE and PAD; further research is needed to understand whether the association with DVT is causal. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png JAMA American Medical Association

Association of Varicose Veins With Incident Venous Thromboembolism and Peripheral Artery Disease

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Publisher
American Medical Association
Copyright
Copyright 2018 American Medical Association. All Rights Reserved.
ISSN
0098-7484
eISSN
1538-3598
D.O.I.
10.1001/jama.2018.0246
Publisher site
See Article on Publisher Site

Abstract

Key PointsQuestionAre varicose veins associated with an increased risk of developing deep venous thrombosis (DVT), pulmonary embolism (PE), or peripheral artery disease (PAD)? FindingsIn this retrospective cohort study from Taiwan that included 425 968 adults, the presence of varicose veins was associated with a significantly increased risk of incident DVT (hazard ratio [HR], 5.30), PE (HR, 1.73), and PAD (HR, 1.72). MeaningThis study found a significant association between varicose veins and DVT, and less clear potential associations with PE and PAD; further research is needed to understand whether the association with DVT is causal.

Journal

JAMAAmerican Medical Association

Published: Feb 27, 2018

References

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