Key PointsQuestionWhich dermoscopic criteria represent potent indicators for the diagnosis of melanoma in situ compared with nevi and seborrheic keratoses, solar lentigines, or lichen planus–like keratoses; pigmented superficial basal cell carcinoma; pigmented intraepidermal carcinoma; and Reed nevi? FindingsIn this diagnostic accuracy study of 1285 lesions from 1285 patients, irregular hyperpigmented areas and prominent skin markings represented potent indicators of melanoma in situ compared with atypical nevi. Atypical network, regression, and angulated lines were additional indicators of melanoma in situ compared with all other tumors. MeaningBecause the goal of clinicians is to diagnose melanoma at the earliest possible stage, knowing the dermoscopic indicators of melanoma in situ is of paramount importance.
JAMA Dermatology – American Medical Association
Published: Apr 21, 2018
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