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BK virus-induced severe hemorrhagic cystitis in non-transplant oncology patients: A case series

BK virus-induced severe hemorrhagic cystitis in non-transplant oncology patients: A case series Hemorrhagic cystitis is often a serious condition in cancer patients and can be life threatening despite aggressive treatment measures. The condition may be secondary to infections, radiation or chemotherapy. Oxazaphosphorine alkylating agents, such as cyclophosphamide and ifosfamide, are the most frequent causes of chemotherapy-induced HC in cancer patients. Only a few cases of BK virus-associated hemorrhagic cystitis in non-transplant cancer patients have been reported worldwide. Here, we report two cases of BK-induced HC in non-transplant oncology patients; one patient died due to multi-system failure of unknown etiology, and the other patient was treated successfully with low-dose cidofovir. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Journal of Pediatric Infectious Diseases IOS Press

BK virus-induced severe hemorrhagic cystitis in non-transplant oncology patients: A case series

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Publisher
IOS Press
Copyright
Copyright © 2014 by IOS Press, Inc
ISSN
1305-7707
eISSN
1305-7693
DOI
10.3233/JPI-140435
Publisher site
See Article on Publisher Site

Abstract

Hemorrhagic cystitis is often a serious condition in cancer patients and can be life threatening despite aggressive treatment measures. The condition may be secondary to infections, radiation or chemotherapy. Oxazaphosphorine alkylating agents, such as cyclophosphamide and ifosfamide, are the most frequent causes of chemotherapy-induced HC in cancer patients. Only a few cases of BK virus-associated hemorrhagic cystitis in non-transplant cancer patients have been reported worldwide. Here, we report two cases of BK-induced HC in non-transplant oncology patients; one patient died due to multi-system failure of unknown etiology, and the other patient was treated successfully with low-dose cidofovir.

Journal

Journal of Pediatric Infectious DiseasesIOS Press

Published: Jan 1, 2014

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