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the majority of the lymphoid tissue of the body. There are a number of important features of the gastrointestinal mucosal immune system : the mucosal immune system contains specialized structures ...
. This short review highlights aspects of this finetuned interplay. We also address how deficiencies in mucosal defense can promote disease. First, genetic defects of sensors or effectors of epithelial defense ...
covered with special epithelial layers which support this barrier function. The immune system , associated with mucosal surfaces covering the largest area of the body (200–300 m2), evolved ...
The intestinal immune system and the epithelium are the first line of defense in the gut. Constantly exposed to microorganisms from the environment, the gut has complex defense mechanisms to prevent ...
of the mucosal barrier. The immense expansion and specialization of the immune system is particularly mirrored in the phylogeny, ontogeny, organization, and regulation of the adaptive intraepithelial lymphocytes ...
it shares a number of features with other mucosal tissues, the ocular mucosal system , composed of the conjunctiva, Meibomian glands, and lacrimal glands, is specialized to address the unique needs ...
Abstract The gut mucosal immune system is a critical component of the body's defense against pathogenic organisms, especially those responsible for enteric infections associated with diarrhoeal ...
. To protect the body from foreign Ags, the gastrointestinal mucosa coordinates a specialized immune system in which Peyer's patches (PPs) and mesenteric lymph nodes (MLNs) serve as mucosal immune inductive ...
call on the mucosal immune system in the mucosal tissues to maintain homeostasis of gastrointestinal functions and structure. Abrogation of these mucosal defense mechanisms may lead to alter immunologic ...
immune system is an evolutionarily conserved host defense system with key features being shared between plants, invertebrates, and mammals [1,2]. Innate immune defenses in mammals encompass virtually all ...
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