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, E.V. Grishin, 2015, published in Doklady Akademii Nauk, 2015, Vol. 465, No. 2, pp. 252–254. GENERAL BIOLOGY Biological Activity of a Polypeptide Modulator of TRPV1 Receptor a b b I. A. Dyachenko , Ya ...
to determine, by infusing kinetensin to conscious sheep, the pharmacokinetics and a neurotensin-like biological activity (pancreatic polypeptide response) of kinetensin. Kinetensin was rapidly metabolized ...
artificial enzymes with nearly native enzyme- like activities against a number of non-natural substrates. Combining aspects of de novo design and biological evolution of nature’s enzymes has started ...
of the antimicrobial peptide gramicidin S at several sites. The biological activity of the resulting peptidomimetics could then be effectively controlled by ultraviolet/visible light within strictly defined spatial ...
of the antimicrobial peptide gramicidin S at several sites. The biological activity of the resulting peptidomimetics could then be effectively controlled by ultraviolet/visible light within strictly defined spatial ...
been lacking. Here, we employ two complementary microfluidic platforms to probe the structure– activity relationships of two experimental series of polypeptide antibiotics. We reveal strong correlations ...
was at odds with previously reported results for an ShK diastereomer designated d-allo-ShK, for which significant biological activity had been observed in a similar receptor-blocking assay. As reported, d-allo ...
‐containing peptide models Ac‐(Aib‐Arg‐Aib‐Leu)n‐NH2, n = 1–4, and sequential cationic polypeptides (Arg‐X‐Gly)n, X = Ala, Val, Leu, were prepared and studied for their antimicrobial and hemolytic activity ...
Antimicrobial peptides (also known as genetically encoded peptide antibiotics) are a diverse class of short cationic amphipathic polypeptides that exhibit a broad-spectrum of antimicrobial activities ...
Proper folding is essential for the biological functions of all proteins. The folding process is intrinsically error-prone, and the misfolding of a polypeptide chain can cause the formation of toxic ...
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