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as a potential fungicidal compound. In this study, we provide the results of a biological activity evaluation using various structures and figures. Literature investigation showed that 1 , 2 , 4 -triazole derivatives ...
BackgroundThe increase in resistance of pathogenic organisms to the available chemotherapeutic agents are critical challenges in drug design and development, motivating researchers to look for novel ...
Syntheses of 2 ‐aminothiazole derivatives of 4 ‐hydroxy‐chromene‐ 2 ‐one 2c–10c are reported in this paper. These compounds 2c–10c were prepared from 3‐( 2 ‐bromoacetyl)‐ 4 ‐hydroxy‐chromene‐ 2 ‐one 1 ...
some guidance for development of some novel benzimidazole‐based antifungal lead structures . J. Heterocyclic Chem., 2010. INTRODUCTION Thiazolidin‐ 4 ‐ones constitute an important class of heterocyclic ...
This work describes the synthesis and antifungal evaluation of 5‐arylidene‐(Z)‐ 2 ‐(1,1‐dicyanomethylene)‐1,3‐thiazol‐ 4 ‐ones 5 obtained from the reaction of 2 ‐(1,1‐dicyanomethylene)‐1,3‐thiazol‐ 4 ‐one 3 ...
The aim of this study involves the synthesis of novel heterocyclic scaffolds containing quinoline moiety and studying their role as antimicrobial agents. 4 ‐hydroxy‐6‐phenyl‐2H‐pyrano[3,2‐c]quinoline ...
. The structure of newly compounds was characterized by 1H-NMR, IR and elemental analysis. The aim of the work is synthesis of some novel azo dye from 1,2-dihydro- 4 -hydroxy- 2 -oxoquinoline-6-sulfonic acid (3), 4 ...
For the first time, a thiosemicarbazone-type ligand containing a paracetamol structural unit was synthesized. Five new coordination compounds based on copper(II) salts: [Cu(L)CH3COO] ( 1 ), [{Cu(L)Cl} 2 ...
A series of 47 novel N1‐alkylated‐ 2 ‐aryl‐5(6)‐substituted‐1H‐benzimidazoles and their three novel indole analogues were synthesized and evaluated for in vitro antifungal activities against Candida ...
amorolfine is approved for the treatment of dermal mycoses in humans. Inspired by these lead structures , we describe here the synthesis and biological evaluation of 4 -aminopiperidines as a novel chemotype ...
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