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therapy in children and adolescents . Pediatrics 1974;54:668-670. 11. Woolcock AJ: Inhaled drugs in the prevention of asthma . Am Rev Respir Dis 1977;115:191-194. 12. Van Metre TE: Adverse effects ...
-potency drugs such as fluticasone.Most studies in asthmatic children have shown that with doses of inhaled corticosteroid of 0.4 mg/d or less, irrespective of drug or delivery device , there is no evidence ...
for exercise-induced asthma (EIA).1 The inhaled route of administration is preferred, whereas oral administration is used mainly with young children who have difficulty in coordinating the inhalation and release ...
to inhale forcefully and deeply through the mouth.30 Turbuhaler devices were identical in appearance, and the drug delivery was indistinguishable by taste or smell. The dose of budesonide administered was 2 ...
Abstract Context Long-acting β2-agonists are prescribed for patients with persistent asthma and are sometimes used without inhaled corticosteroids (ICSs). No evidence exists, however, to support ...
. (Arch Intern Med 1982;142:2163-2172) References 1. Morrow PE: Aerosol characterization and deposition. Am Rev Respir Dis 1974;110:88-99. 2. Hatch TF, Gross P: Pulmonary Deposition and Retention of Inhaled ...
by the US Food and Drug Administration (FDA)3 (2). Exhaled breath contains both volatile and nonvolatile compounds. Major components of breath are water vapor and inhaled air that has not reached alveoli ...
of previous exposure from a measurement of exhaled breath. It differs from previous models in considering long-term inhalation at low or moderate concentrations rather than instantaneous intake (as in drug ...
gaps . OF collection Easy, noninvasive; no need for privacy; sex neutral Between- and within- device variability in drug recovery, stability, volume collected; dry mouth reduces OF volume; stimulation can ...
aerosolized NPs similar to inhalation exposure of humans (Ji et al., 2017; Zanoni et al., 2016). Similarly, several research groups have developed tumor spheroid models to study tumor growth, drug testing ...
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