Access the full text.
Sign up today, get unlimited access with DeepDyve Pro!
solid dispersion (ASD) of a rapidly crystallizing drug, nisoldipine. Also, ASD preparation from lab scale formulation technique to scalable spray drying technique followed by oral bioavailability study ...
permeability, and SD stability.MethodA ternary SD containing nisoldipine as drug and PVP K30, poloxamer 188 as the carrier was prepared by hot melt mixing, solvent evaporation by rotary vacuum evaporator ...
and stabilization of amorphous precipitates formed following drug release.MethodsTernary ASDs with ritonavir, copovidone and surfactants (30:70:5 w/w/w) were prepared by rotary evaporation . ASD release performance ...
PurposeThe use of two solvent-casted film methods to select optimal polymer compositions for amorphous solid dispersions prepared to support preclinical pharmacokinetic and toxicology studies ...
(PVAP) and hypromellose (hydroxypropyl methylcellulose, HPMC). The solid dispersions were prepared using two different solvent methods: rotary evaporation (rotavap) and fluid bed drug layering on sugar ...
(PVP K30) and polyethylene glycol (PEG 4000). Methods: Solid dispersions (SDs) between CA and PVP K30/PEG 4000 were formed by dissolving both compounds in a common solvent, methanol, which were rotary ...
PurposeTo understand how surfactants affect drug release from ternary amorphous solid dispersions (ASDs), and to investigate different mechanisms of release enhancement.MethodsTernary ASDs containing ...
of preparation methods on surface/bulk structural relaxation and glass fragility of amorphous solid dispersions . Int J Pharm 2012 ; 422 : 170 – 178 . Google Scholar Crossref Search ADS PubMed WorldCat Al-Obaidi H ...
≥CMCAB > PAA Stability of solid dispersions towards crystallization Attempts to prepare neat amorphous naringenin and quercetin via rotary evaporation failed. A thin film of amorphous naringenin could ...
solid dispersions (SDs),[7–9] liposomes,[10–12] micelles[13–16] and nanoparticles.[17,18] Among these, SD is the most promising method due to its relatively simple preparation technique. It has become one ...
Access the full text.
Sign up today, get unlimited access with DeepDyve Pro!