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. Chitosan exhibits myriad biological actions, namely hypocholesterolemic, antimicrobial and wound healing properties . Low toxicity coupled with wide applicability makes it a promising candidate not only ...
structure— property correlations during preclinical development. We describe two examples of our research on pharmaceutical polymer development: narrow molecular weight distribution (MWD) homopolymeric ...
biological polymers with biophysical properties very similar to poly -ethylene glycol (PEG), whose chemical conjugation to drugs is an established method for plasma half-life extension. In contrast, PAS ...
immunoselected using GST fusion protein- or GST-coupled Sepharose as affinity matrices. To this end, a DNA [232 (SmaI)–701 (SmaI), encoding amino acids 7–162] of mouse Dnmt3a (accesion no. AF068625) and a DNA [1 ...
are calculated. The solubility of the nucleotides increases upon increasing the DNA nucleotide chain. ILs with non-polar side-chain amino acid anions form stronger interactions with the nucleotides, as compared ...
. ( 2006 ) Spontaneous formation of vesicles and dispersed cubic and hexagonal particles in amino acid -based catanionic surfactant systems . Langmuir 22 : 5588 – 5596 . Google Scholar Crossref Search ADS ...
throughout a protein. In contrast, linker function heavily depends on length while chemical diversity is limited to combinations of amino acid repeats that confer distinct biophysical properties , for instance ...
Abstract Background: The inherent fluorescent properties of nucleosides, nucleotides, and nucleic acids are limited, and thus the need has arisen for fluorescent labeling of these molecules ...
) Conformational analysis of DNA – poly -l-lysine complexes by optical rotatory dispersion. J. Mol. Biol. , 35, 241–245. Google Scholar 12 Shapiro,J.T., Leng,M. and Felsenfeld,G. ( 1969) Deoxyribonucleic acid ...
. In DNA gel blot analysis, two to four bands hybridizing to the 3′ half of the Ahm1 gene (corresponding to amino acid positions 332 to 527) were detected when the genomic DNA was first digested with BamHI ...
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