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are clouded by use of an antibody (C20) that lacks specificity for the erythropoietin receptor [32, 33]. In addition to direct effects on tumor cells, erythropoietin might stimulate tumor progression through ...
Text WorldCat 17 M Henke , R Laszig, C Rube et al. Erythropoietin to treat head and neck cancer patients with anaemia undergoing radiotherapy: randomised, double-blind, placebo-controlled trial . Lancet ...
Department and from ENHANCE, a previously reported [3] multicenter Phase III trial of epoetin beta in 351 patients receiving radiotherapy for head and neck cancer. All ENHANCE samples were among 154 tumors ...
. The early closure of the Goldberg [41] trial for patients with head and neck cancer was predicated on a detrimental effect on locoregional control and a trend toward a shorter survival duration in patients ...
overall and disease-free survival, greater recurrence, and less locoregional control in head and neck carcinoma, cervical carcinoma, and soft-tissue sarcoma. In view of the deleterious effect of hypoxia ...
European trial (MF4449), Henke et al. [50] investigated the effects of anemia correction with epo-etin beta on the outcome of curative radiotherapy among patients with head and neck cancer. Three hundred ...
or anoxia [26]. Similarly, Becker et al. found a significant (p = 0.0001) association between severe anemia and poor tumor oxygenation in patients with head and neck squamous cell carcinomas [27]. Data from ...
had a protective effect against several forms of neuronal damage occurring in stroke, head trauma, epilepsy, and autoimmune encephalitis.Astrocytes and neurons also can produce erythropoietin under ...
Crossref Search ADS PubMed WorldCat 26 Prince ME . Identification of a subpopulation of cells with cancer stem cell properties in head and neck squamous cell carcinoma . Proc Natl Acad Sci U S A 2007 ; 104 ...
correlations between anemia and shorter survival times in patients with a wide variety of solid tumors and hematologic malignancies, including lung, ovarian, breast, and head / neck cancers, non-Hodgkin's lymphoma ...
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