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Human aging is associated with loss of function and regenerative capacity. Human bone marrow derived mesenchymal stromal cells (hMSCs) are involved in tissue regeneration, evidenced by their capacity ...
cellular hallmarks of aging . Lower levels of GATA6 expression were also found in cells harvested from younger mice or lower passage cultures. Our findings suggest that GATA6 is a critical regulator increased ...
a wide range of factors. Donor age seems to impact the secreted protein profile and proliferation ability of BM-MSCs. Here, we investigate if cells from full-term birth donors will reduce the variability ...
to suppress T- cell proliferation and polarize macrophages toward an M2 anti-inflammatory phenotype. MATERIALS AND METHODS Cell culture Mesenchymal stromal cells hMSCs were purchased from Lonza and maintained ...
the accumulation of oxidative damage or “fitness” of human BMSC from donors of various ages was investigated. Measuring various age and senescence markers used routinely to characterize the aging of somatic cells ...
Guardia R , Lopez-Millan B, Lavoie JR et al. . Detailed characterization of mesenchymal stem/ stromal cells from a large cohort of AML patients demonstrates a definitive link to treatment outcomes . Stem ...
Allogenic use , low; , medium; , high. Open in new tab Comparison of mesenchymal stromal /stem cells (MSCs) from different sources with reference to different parameters: bone marrow-derived MSCs, adipose ...
, there are also differences associated with obtaining them from individual donors . Among the cells isolated from the bone marrow from donors of different ages and sexes, up to 12-fold differences in the rate ...
from George et al. [3] now establishes that a wide range of stem cell types differentially promote clot formation via varying levels of TF expression, thereby advocating for the implementation ...
-Transferase Pi 1; LC-MSMS, liquid chromatography-tandem mass spectrometry; MS, multiple sclerosis; MSC, mesenchymal stromal cells ; MS-MSC, mesenchymal stromal cells from patients with multiple sclerosis; SOD1 ...
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