Access the full text.
Sign up today, get unlimited access with DeepDyve Pro!
triglyceride metabolism such as PPARα, RORα, LXR and SREBP‐1c and this supports its function. Insulin and interleukins regulate APOA5 gene expression and provide novel clues for the role of this apolipoprotein ...
Apolipoprotein A5 (apoA5) has an important role in lipid metabolism, specifically for triglyceride ‐ rich lipoproteins. Recently, evidence has emerged for an association between genetic variability ...
as that in familial lipoprotein lipase deficiency (34)(35). Apo C3, on the other hand, is an inhibitor of lipoprotein lipase (32). Apo A5 now joins these as a metabolic regulator of triglyceride clearance, but one ...
Apolipoprotein A5 (apoA5) has been identified to play an important role in lipid metabolism, specifically in triglyceride (TG) and TG- rich lipoproteins (TRLs) metabolism. Numerous evidence has ...
is important for the regulation of triglyceride - rich lipoproteins in humans and binds to the VLDL receptor, LDL receptor, and LDL-receptor-related protein. This process allows apo E to compensate partially ...
Abstract Background: Apolipoprotein A5 (ApoA5) originally gained attention as a regulator of serum triglyceride concentrations through transgenic mouse studies. Our group recently developed the first ...
Smarca2 AK011935 Negative regulation of cell proliferation 2.65 ± 0.23 Apoa5 AK050280 Triglyceride transport 3.17 ± 0.19 Cbr1 U31966 Carbonyl reductase (NADPH) 3.12 ± 0.31 ...
to resolve the role of SORT1 which encodes sortilin from it's neighbours (45). Parallel functional studies have implicated sortilin as a novel regulator of lipoprotein production in the liver (46), thereby ...
growth and bone development by regulating the transcription of endocrine IGF-1 components. PMID: 26402843 AST (0.284, 0.000356) Muscle triglycerides (−0.685, 0.00654) HOMAIR_MagicEur (1.88) FPG (−0.203 ...
a role in the transcription of lipogenic genes in hepatocytes and thereby affects overall apolipoprotein B (ApoB) particle accumulation, alters particle composition and regulates very large density ...
Access the full text.
Sign up today, get unlimited access with DeepDyve Pro!