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pancreatic β-cells [1]. A number of signalling molecules have been implicated in regulating secretion. For example, insulin release from β-cells is affected by Hedgehog proteins [12], Wnts [13] and BMPs [14 ...
insulin secretion after treatment. These data establish molecular mechanisms underlying persistent adrenergic stimulation in hyperfunctional fetal islets and identify a subset of genes dysregulated ...
in normal and scleroderma human dermal fibroblast lines and studied the involvement of serine/threonine kinase B/ protein kinase B (Akt) in this response. Dermal fibroblast lines were stimulated with TNF-α ...
was investigated. B cells cultured with EtxB, but not a non‐receptor binding mutant protein , EtxB(G33D), caused the activation of the extracellular signal‐regulated kinase (Erk) forms of mitogen‐activated protein ...
and relatively few studies examined the biological role of EVs in the brain. Neuron-derived EVs. In vitro rat primary cultured neurons release EVs containing L1 cell adhesion molecules, GPI - anchored prion proteins ...
, such as bioethanol– by far the largest volume fermentation product. It is also used for the production of several recombinant proteins , for example, human insulin , hepatitis vaccines, and human papillomavirus (HPV ...
of receptors and coupling proteins involved in signal transduction pathways and lipid metabolism. These include the GPI -linked fatty acid transport protein CD36, the α1- and β-adrenergic receptors, membrane ...
of the receptor with two subunits (A and B) linked by the disulfide bridge which originally formed the loop,” as is “well established in the cases of several proteins including insulin ” and “reduction ...
the loop,” as is “well established in the cases of several proteins including insulin ” and “reduction of the disulfide bridge allows release of the water-soluble A-subunit” (6) (Figure 1A). This concept ...
., Campbell, A. S., Fraser-Reid, B., Grusby, M. J. and Tachado, S. D. 1999. CD1d-restricted Immunoglobulin G formation to GPI - anchored antigens mediated by NKT cells. Science 283: 225. Google Scholar 14 ...
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