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of treatment activity in order to individualise dosing during therapy. Hypertension (HTN) was the first biomarker to be favourably associated with outcome in sunitinib ‐treated patients . In a pooled database ...
Aims and backgroundClinical practice shows significant differences in treatment outcomes and toxicity of sunitinib across patients. This retrospective study assessed early predictive markers ...
The objective of this study was to comprehensively evaluate the clinical outcomes of 110 consecutive Japanese patients who received at least two cycles of sunitinib as first-line therapy ...
for the treatment of metastatic Renal Cell Carcinoma (RCC)We evaluated the association of sunitinib induced hypertension with clinical outcomes in patients with RCC.Methods: We consecutively included 67 RCC patients ...
Clinical practice shows significant differences in treatment outcomes across patients treated with cabozantinib for metastatic renal cell carcinoma (mRCC). It is not known whether cabozantinib ...
Learning Objectives Describe the association between risk factors for renal cell carcinoma and the outcome of sunitinib treatment for metastatic disease. Explain the impact of active smoking ...
continuous dosing as first‐line therapy for metastatic renal cell cancer]) compared the outcomes for treatment ‐naive patients with advanced RCC who received sunitinib , schedule 4/2 versus CDD [25]. The median ...
and angiogenic factors in patients with advanced non-clear cell renal cell carcinoma (nccRCC) treated with sunitinib . No association was found between hypertension and patient outcomes . However, a group ...
study, in which total PFS did not differ significantly between the treatment sorafenib‐ sunitinib and sunitinib ‐sorafenib sequences in treatment ‐naive patients with metastatic RCC (mPFS, 12.5 vs. 14.9 ...
with pathway inhibition in tumors. It is also critical to state that MBTs can only be used as predictors for outcome after initiating treatment . Therefore, they can be taken as surrogates for further clinical ...
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