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. We hypothesized that other ABC proteins, such as members of the G subfamily, are also involved in the BBB clearance of Aβ. We therefore investigated the roles of ABCG2 ( BCRP ) and ABCG4 in the efflux ...
). In fact, the expression of ABCs may significantly vary among individuals and thus affects the efficacy of drug treatment (7). The human ABC transporters are encoded by a large transporter gene superfamily ...
and Abcg2 /breast cancer resistance protein [ Bcrp ]), iron-sulfur cluster binding (Abce1), peroxisomal fatty-acyl-CoA transport (Abcd1), protein homodimerization ( Abcg4 ), and phospholipid efflux (e.g., Abca7 ...
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