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A size polymorphism (K IV VNTR) and largely unknown sequence variation in the apolipoprotein (a) [apo(a)] gene on chromosome 6q26–q27 together determine most of the extreme variation in apo ...
) (author's (J. E .) data (56, 57)). FIGURE 1. View largeDownload slide Comparison of apolipoprotein (apo) ε gene frequencies determined by protein (apo E ) electrophoresis in three US studies: 1) Framingham ...
. The study on the effects of apolipoprotein E gene polymorphism on serum lipids and its frequency distribution in Beijing natural population. J Cardiovascul Pulmon Dis (Chin). 2002;21:193-197Google Scholar 78 ...
, Cayapa Indians, fertility Introduction Apolipoprotein E (APOE = gene , apoE = protein) plays a central role in plasma lipoprotein metabolism and in lipid transport within tissues; it is also involved ...
familial Alzheimer's disease locus. Science.1995;269:973-977.Google Scholar 6. Strittmatter WJ, Saunders AM, Schmechel D. et al. Apolipoprotein E : high avidity binding to β-amyloid and increased frequency ...
autosomal dominant Alzheimer disease: prevalence, genetic heterogeneity , and mutation spectrum.Am J Hum Genet.1999;65:664-670.EHCorderAMSaundersNJRischProtective effect of apolipoprotein E type 2 allele ...
AMStrittmatter WJ et al. Gene dose of apolipoprotein E type 4 allele and the risk of Alzheimer's disease in late onset families. Science 1993;261 (5123) 921- 923PubMedGoogle ScholarCrossref 8. Farrer LA Cupples ...
of apolipoprotein B. J Biol Chem 1989 ; 33 : 19754 -19760. 15 Kotze MJ, Peeters AV, Langenhoven E , Wauters JG, Van-Gaal LF. Phenotypic expression and frequency of familial defective apolipoprotein B-100 in Belgian ...
defective apolipoprotein B100 (FDB). Only 3 sequence variants have been described, and they restrict the binding of apolipoprotein B to the LDL receptor (6)(7)(8). A third gene causing ADH is the one coding ...
levels of high -density lipoprotein (HDL) cholesterol (P = 7.12 × 10−140), C-reactive protein (P ...
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