European Molecular Biology Laboratoly 69117 Heidelberg, Germany Manuscript received October 12, 1995 Accepted for publication December 18, 1995 ABSTRACT The Drosophila un.ngless(wg) gene encodes a secreted signaling protein that is required for many separate patterningevents in both embryonic andlarval development. wgfunctionsin the development of the adult structures have been studied using the conditional mutant w$ and also using regulatory mutations of w that reduce larval functions. Herew present evidence thatSternophral (Jib) another g e is regulatory allele of w that affects a subset of larval functions. Sp has both a recessive loss-of-function g component and a gain-of-function component. The loss-of-function component reflects reduction of a wgactivity in the notum and in antenna. The the gain-of-function component apparently leadsectopic to w activity in the dorsal first and second leg disc and thereby generates the dominant phenotype. Jib g Jib and other w alleles show a complex pattern of complementation. W present evidence that these g e genetic propertiesare due to transvection. These results have implications for the genetic definition of a null allele at loci subject to transvection. HE Drosophila wingless (wg) gene is required for many patterning events during embryogenesis and during larval development (reviewed by KLINGENSMITH and
Genetics – Genetics Society of America
Published: Apr 1, 1996
It’s your single place to instantly
discover and read the research
that matters to you.
Enjoy affordable access to
over 18 million articles from more than
15,000 peer-reviewed journals.
All for just $49/month
Query the DeepDyve database, plus search all of PubMed and Google Scholar seamlessly
Save any article or search result from DeepDyve, PubMed, and Google Scholar... all in one place.
Get unlimited, online access to over 18 million full-text articles from more than 15,000 scientific journals.
Read from thousands of the leading scholarly journals from SpringerNature, Elsevier, Wiley-Blackwell, Oxford University Press and more.
All the latest content is available, no embargo periods.
“Hi guys, I cannot tell you how much I love this resource. Incredible. I really believe you've hit the nail on the head with this site in regards to solving the research-purchase issue.”Daniel C.
“Whoa! It’s like Spotify but for academic articles.”@Phil_Robichaud
“I must say, @deepdyve is a fabulous solution to the independent researcher's problem of #access to #information.”@deepthiw
“My last article couldn't be possible without the platform @deepdyve that makes journal papers cheaper.”@JoseServera