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INTRODUCTION OPULATIONS of Drosophila pseudoobscura inhabiting isolated mountain fests in the Death Valley region are highly variable with respect to gene arrangement as well as to gene content of the chromosomes. and The first article of the esent series (DOBZHANSKY QUEAL1938) dealt with the variability of the gene arrangement; the results of observations on the genic variation are to be repted here. The source of the material and the collecting methods have been described in the publication just quoted and need not be repeated, since the same samples of flies were used in both studies. Our experiments on the genic variation are confined to the third chromosome, although the species has five chromosome pairs. The reasons f this choice are purely technical: esence in the third chromosome of favable gene markers associated with inversions facilitates the experimentation. Our results are essentially similar (1937) and may be regarded to those recently published by STURTEVANT as an extension of the latter. We are indebted to Messrs. EDWARD HELD and G. T. RUDKIN who have shared with us the routine wk involved in conducting the experiments described in this article. DETECTION O F THE CONCEALED GENIC VARIABILITY The samples of flies http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Genetics Genetics Society of America

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