Manuscript received September 26, 1995 Accepted for publication November 29, 1995 ABSTRACT Fstatistics are functions of probabilities of identity in state. These values Expected values of WRIGHTâS may be quite different under an infinite allele model and under stepwise mutation processes such as those occurring at microsatellite loci. However,a relationship between the probability of identity in state in stepwise mutation models and the distribution of coalescence times can bededuced from the relationship between probabilities of identity by descent and the distribution of coalescence times. The values of F,,and FsTcan be computed using this property. Examination of the conditional probability of identity in state given some coalescence time and of the distribution of coalescence times are also useful for explaining the properties of F,,and FST high mutation rate loci, as shown here in an island model of at population structure. he estimation of WRIGHTâS Fstatistics is standard practice (e.g., WEIR1990) and has multiple uses (e.g., HARTL and CLARK 1989; SLATKIN 1993). Most discussions of their properties have been based on the values of probabilities of identity by descent in the infinite allele model. In a recent paper SLATKIN (1995) has emphasized that such theory may not be appropriate for
Genetics – Genetics Society of America
Published: Apr 1, 1996
It’s your single place to instantly
discover and read the research
that matters to you.
Enjoy affordable access to
over 18 million articles from more than
15,000 peer-reviewed journals.
All for just $49/month
Query the DeepDyve database, plus search all of PubMed and Google Scholar seamlessly
Save any article or search result from DeepDyve, PubMed, and Google Scholar... all in one place.
Get unlimited, online access to over 18 million full-text articles from more than 15,000 scientific journals.
Read from thousands of the leading scholarly journals from SpringerNature, Elsevier, Wiley-Blackwell, Oxford University Press and more.
All the latest content is available, no embargo periods.
“Hi guys, I cannot tell you how much I love this resource. Incredible. I really believe you've hit the nail on the head with this site in regards to solving the research-purchase issue.”Daniel C.
“Whoa! It’s like Spotify but for academic articles.”@Phil_Robichaud
“I must say, @deepdyve is a fabulous solution to the independent researcher's problem of #access to #information.”@deepthiw
“My last article couldn't be possible without the platform @deepdyve that makes journal papers cheaper.”@JoseServera