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Whether viable and dead probiotic are equally efficacious?

Whether viable and dead probiotic are equally efficacious? PurposeConsumer inclination towards probiotic foods has been stimulated due to well-documented evidence of health benefits of probiotic-containing products and consumer demand for natural products. It is assumed that the viability and metabolic activities of probiotics are essential for extending health benefits and for successful marketing of probiotics as a functional food. The purpose of this paper is to demonstrate that even dead or inactivated probiotic cells could extend health benefits, indicating that probiotic viability is not always necessary for exhibiting health benefits.Design/methodology/approachAttempt has been made to review the literature on the status of probiotic foods available in the world market, their impact on the gut flora and the various factors affecting their viability. Both review and research papers related to efficacy of inactivated, killed or dead probiotic cells towards health benefits have been considered. Keywords used for data search included efficacy of viable or killed, inactivated probiotic cells.FindingsThe reviewed literature indicated that inactivated, killed or dead probiotic cells also possess functional properties but live cells are more efficacious. All live probiotic cultures are not equally efficacious, and accordingly, dead or inactivated cells did not demonstrate functional properties to extend health benefits to all diseases.Originality/valueCapability of non-viable microorganisms to confer health benefits may attract food manufacturers owing to certain advantages over live probiotics such as longer shelf-life, handling and transportation and reduced requirements for refrigerated storage and inclusion of non-bacterial, biologically active metabolites present in fermented milks’ fraction as dried powders to food matrixes may result in the development of new functional foods. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Nutrition & Food Science Emerald Publishing

Whether viable and dead probiotic are equally efficacious?

Sarkar, S.
Nutrition & Food Science , Volume 48 (2): 16 – Mar 12, 2018
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Publisher
Emerald Publishing
Copyright
Copyright © Emerald Group Publishing Limited
ISSN
0034-6659
DOI
10.1108/NFS-07-2017-0151
Publisher site
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Abstract

PurposeConsumer inclination towards probiotic foods has been stimulated due to well-documented evidence of health benefits of probiotic-containing products and consumer demand for natural products. It is assumed that the viability and metabolic activities of probiotics are essential for extending health benefits and for successful marketing of probiotics as a functional food. The purpose of this paper is to demonstrate that even dead or inactivated probiotic cells could extend health benefits, indicating that probiotic viability is not always necessary for exhibiting health benefits.Design/methodology/approachAttempt has been made to review the literature on the status of probiotic foods available in the world market, their impact on the gut flora and the various factors affecting their viability. Both review and research papers related to efficacy of inactivated, killed or dead probiotic cells towards health benefits have been considered. Keywords used for data search included efficacy of viable or killed, inactivated probiotic cells.FindingsThe reviewed literature indicated that inactivated, killed or dead probiotic cells also possess functional properties but live cells are more efficacious. All live probiotic cultures are not equally efficacious, and accordingly, dead or inactivated cells did not demonstrate functional properties to extend health benefits to all diseases.Originality/valueCapability of non-viable microorganisms to confer health benefits may attract food manufacturers owing to certain advantages over live probiotics such as longer shelf-life, handling and transportation and reduced requirements for refrigerated storage and inclusion of non-bacterial, biologically active metabolites present in fermented milks’ fraction as dried powders to food matrixes may result in the development of new functional foods.

Journal

Nutrition & Food Science – Emerald Publishing

Published: Mar 12, 2018

References

  • The probiotic paradox: live and dead cells are biological response modifiers
  • In vitro cholesterol assimilation and functional enzymatic activities of putative probiotic Lactobacillus sp. isolated from fermented foods/beverages of North West India
  • National survey outcomes on commercial probiotic food supplements in Italy
  • Comparison between killed and living probiotic usage versus placebo for the prevention of necrotizing enterocolitis and sepsis in neonates
  • Market assessment and product evaluation of probiotic containing dietary supplements available in Bangladesh market
  • Commensal microbiota and myelin autoantigen cooperate to trigger autoimmune demyelination
  • Probiotic mechanisms of action
  • Prospects, technological aspects and limitations of probiotics – a worldwide review
  • Engineering robust lactic acid bacteria
  • Cell surface-associated compounds of probiotic lactobacilli sustain the strain-specificity dogma
  • Influence of osmotic stress and encapsulating materials on the stability of autochthonous Lactobacillus plantarum after spray drying
  • The buffering capacity of probiotic yogurt
  • Recommendations for the viability assessment of probiotics as concentrated cultures and in food matrices
  • Health benefits of probiotics: are mixtures more effective than single strains?
  • Cell surface of Lactococcus lactis is covered by a protective polysaccharide pellicle
  • Pretreatment with a heat-killed probiotic modulates monocyte chemoattractant protein-1 and reduces the pathogenicity of influenza and enterovirus 71 infections
  • Production conditions affect the in vitro anti-tumoral effects of a high concentration multi-strain probiotic preparation
  • Characterization of the intestinal microbiota and its interaction with probiotics and health impacts
  • Variability in the content of Lactobacillus casei in different commercial lots of fermented milks
  • Mechanisms and therapeutic effectiveness of lactobacilli
  • Immunomodulatory effect of non-viable components of probiotic culture stimulated with heat-inactivated Escherichia coli and Bacillus cereus on holoxenic mice
  • Probiotic fermented foods for health benefits
  • Microbiological evaluation of commercial probiotic products available in the USA in 2009
  • Assessment of the effect of stress-tolerance acquisition on some basic characteristics of specific probiotics
  • Scientific opinion on the substantiation of health claims related to live yoghurt cultures and improved lactose digestion
    EFSA
  • Food matrices and cell conditions influence survival of Lactobacillus rhamnosus GG under heat stresses and during storage
  • Guidelines for the evaluation of probiotics in food
    FAO/WHO
  • The influence of different combinations of probiotic bacteria and fermentation temperatures on the microbiological and physicochemical characteristics of fermented lactic beverages containing soybean hydrosoluble extract during refrigerated storage”, cienc
  • Sources, isolation, characterisation and evaluation of probiotics
  • Evaluation of commercial probiotic products
  • Towards a maximal cell survival in convective thermal drying processes
  • Functional microorganisms for functional food quality
  • Anti-influenza virus effects of both live and non-live Lactobacillus acidophilus L-92 accompanied by the activation of innate immunity
  • A review of the advancements in probiotic delivery: conventional vs. non-conventional formulations for intestinal flora supplementation
  • Functional food and nondairy probiotic food development: trends, concepts and products
  • Manufacturing process influences properties of probiotic bacteria
  • Bifidobacterium longum lysate, a new ingredient for reactive skin
  • Comparison of effects of live- and dead cell from potential probiotic lactic acid bacteria
  • Probiotics in Clostridium difficile infection: reviewing the need for a multi-strain probiotic
  • Expert consensus document. The international scientific association for probiotics and prebiotics consensus statement on the scope and appropriate use of the term probiotic
  • Oral intake of heat-killed Lactobacillus plantarum L-137 decreases the incidence of upper respiratory tract infection in healthy subjects with high levels of psychological stress
  • Lactobacillus rhamnosus cell lysate in the management of resistant childhood atopic eczema