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The addition of cactus flour (Opuntia ficus indica) to the Western-style diet attenuates the onset of metabolic disorders in rats

The addition of cactus flour (Opuntia ficus indica) to the Western-style diet attenuates the... The purpose of this study is to investigate the effect of a 15-week dietary intake of cactus flour on metabolic parameters, body weight and dietary intake of rats.Design/methodology/approachMale Wistar rats were divided into four experimental groups (n = 8-10): control or westernized diets added or not of cactus flour. The following parameters were evaluated during the period of dietary manipulation: body weight, food intake, glycemic and lipid profile (oral glucose tolerance test, metabolic parameters, hepatic and muscular glycogen dosage), visceral and body fat (relative weight to body weight). Data were analyzed using Graphpad Prism®5, p = 0.05.FindingsAnimals fed on a Western-style diet together with flour cactus presented lower weight gain (335.7 ± 20.0, p = 0.05) over the evaluated period, even when the volume of food intake was not different among the groups. The addition of cactus flour to a Western-style diet appears to lower glucose levels at 30 and 60 min (p = 0.05), as shown in the glucose tolerance curve. There was a downward trend does fat stores, cholesterol levels and triglycerides. Therefore, it was concluded that this addition cactus flour is effective even when the diet is hyperlipidic, demonstrating its ability to attenuate risk parameters for the occurrence of metabolic syndromes such as sub fraction high cholesterol levels and glucose tolerance.Originality/valueThe addition of functional foods to diets may work to improve the harmful effects of this type of diet. Opuntia ficus indica has high nutritional value and has hypoglycemic and hypolipemic properties besides being antioxidant. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Nutrition & Food Science Emerald Publishing

The addition of cactus flour (Opuntia ficus indica) to the Western-style diet attenuates the onset of metabolic disorders in rats

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Publisher
Emerald Publishing
Copyright
© Emerald Publishing Limited
ISSN
0034-6659
DOI
10.1108/nfs-08-2018-0231
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Abstract

The purpose of this study is to investigate the effect of a 15-week dietary intake of cactus flour on metabolic parameters, body weight and dietary intake of rats.Design/methodology/approachMale Wistar rats were divided into four experimental groups (n = 8-10): control or westernized diets added or not of cactus flour. The following parameters were evaluated during the period of dietary manipulation: body weight, food intake, glycemic and lipid profile (oral glucose tolerance test, metabolic parameters, hepatic and muscular glycogen dosage), visceral and body fat (relative weight to body weight). Data were analyzed using Graphpad Prism®5, p = 0.05.FindingsAnimals fed on a Western-style diet together with flour cactus presented lower weight gain (335.7 ± 20.0, p = 0.05) over the evaluated period, even when the volume of food intake was not different among the groups. The addition of cactus flour to a Western-style diet appears to lower glucose levels at 30 and 60 min (p = 0.05), as shown in the glucose tolerance curve. There was a downward trend does fat stores, cholesterol levels and triglycerides. Therefore, it was concluded that this addition cactus flour is effective even when the diet is hyperlipidic, demonstrating its ability to attenuate risk parameters for the occurrence of metabolic syndromes such as sub fraction high cholesterol levels and glucose tolerance.Originality/valueThe addition of functional foods to diets may work to improve the harmful effects of this type of diet. Opuntia ficus indica has high nutritional value and has hypoglycemic and hypolipemic properties besides being antioxidant.

Journal

Nutrition & Food Science – Emerald Publishing

Published: Aug 12, 2019

Keywords: Body fat; Glucose tolerance; Opuntia fícus indica; Rats; Western-style diet

References

  • The effect of soluble fiber supplementation on metabolic syndrome profile among newly diagnosed type 2 diabetes patients
    Abutair, A.S.; Naser, I.A.; Hamed, A.T.
  • Anti-hyperglycemic effect of opuntia streptacantha lem
    Andrade-Cetto, A.; Wiedenfeld, H.
  • By-products of opuntia ficus-indica as a source of antioxidant dietary fiber
    Bensadon, S.; Hervert-Hernandez, D.; Sayago-Ayerdi, S.G.; Goni, I.
  • Maternal fat, but not lean, mass is increased among overweight/obese women with excess gestational weight gain
    Berggren, E.K.; Groh-Wargo, S.; Presley, L.; Hauguel-De Mouzon, S.; Catalano, P.M.
  • Guar gum: a miracle therapy for hypercholesterolemia, hyperglycemia and obesity
    Butt, M.S.; Shahzadi, N.; Sharif, M.K.; Nasir, M.
  • Comparative evaluation of two different opuntia ficus-indica extracts for blood sugar lowering effects in rats
    Butterweck, V.; Semlin, L.; Feistel, B.; Pischel, I.; Bauer, K.; Verspohl, E.J.
  • The determination of glycogen in liver and muscle by use of anthrone reagent
    Carroll, N.V.; Longley, R.W.; Roe, J.H.
  • Origins and evolution of the Western diet: health implications for the 21st century
    Cordain, L.; Eaton, S.B.; Sebastian, A.; Mann, N.; Lindeberg, S.; Watkins, B.A.; O’keefe, J.H.; Brand-Miller, J.
  • Abdominal adiposity, insulin and bone quality in young male rats fed a high-fat diet containing soybean or canola oil
    Costa, C.A.; Carlos, A.S.; Dos Santos Ade, S.; Monteiro, A.M.; Moura, E.G.; Nascimento-Saba, C.C.
  • Biochemical and hematological parameters of wistar rats and swiss mice in the professor thomas george animal laboratory
    Dantas, B.D.a.; , S.O.R.
  • Nopal cactus (Opuntia ficus-indica) as a source of bioactive compounds for nutrition, health and disease
    El-Mostafa, K.; El Kharrassi, Y.; Badreddine, A.; Andreoletti, P.; Vamecq, J.; El Kebbaj, M.S.; Latruffe, N.; Lizard, G.; Nasser, B.; Cherkaoui-Malki, M.
  • Fiber and functional gastrointestinal disorders
    Eswaran, S.; Muir, J.; Chey, W.D.
  • Prickly pear (Opuntia sp.) pectin alters hepatic cholesterol metabolism without affecting cholesterol absorption in guinea pigs fed a hypercholesterolemic diet
    Fernandez, M.L.; Lin, E.C.; Trejo, A.; Mcnamara, D.J.
  • Pectin isolated from prickly pear (Opuntia sp.) modifies low density lipoprotein metabolism in cholesterol-fed guinea pigs
    Fernandez, M.L.; Trejo, A.; Mcnamara, D.J.
  • Early exposure of dams to a westernized diet has long-term consequences on food intake and physiometabolic homeostasis of the rat offspring
    Ferro Cavalcante, T.C.; Marcelino Da Silva, A.A.; Lira, M.C.; Do Amaral Almeida, L.C.; Marques, A.P.; Do Nascimento, E.
  • A simple method for the isolation and purification of total lipides from animal tissues
    Folch, J.; Lees, M.S.; Stanley, G.H.
  • Estimation of the concentration of low-density lipoprotein cholesterol in plasma, without use of the preparative ultracentrifuge
    Friedewald, W.T.; Levy, R.I.; Fredrickson, D.S.
  • A natural fiber complex reduces body weight in the overweight and obese: a double-blind, randomized, placebo-controlled study
    Grube, B.; Chong, P.W.; Lau, K.Z.; Orzechowski, H.D.
  • Opuntia humifusa stems lower blood glucose and cholesterol levels in streptozotocin-induced diabetic rats
    Hahm, S.W.; Park, J.; Son, Y.S.
  • GSK3 and its interactions with the PI3K/AKT/mTOR signalling network
    Hermida, M.A.; Dinesh Kumar, J.; Leslie, N.R.
  • Maternal high-fat diet impairs glucose metabolism, beta-cell function and proliferation in the second generation of offspring rats
    Huang, Y.H.; Ye, T.T.; Liu, C.X.; Wang, L.; Chen, Y.W.; Dong, Y.
  • Glycemic index and glycemic load in the opuntia ficus-indica fruit
    Ibarra-Salas, M.J.; Novelo-Huerta, H.I.; De Leon-Salas, M.A.; Sanchez-Murillo, M.E.; Mata-Obregon, M.D.C.; Garza-Juarez, A.J.
  • Nutrition transition and obesity among teenagers and young adults in South asia
    Jayawardena, R.; Ranasinghe, P.; Wijayabandara, M.; Hills, A.P.; Misra, A.
  • Opuntia ficus-indica seed attenuates hepatic steatosis and promotes M2 macrophage polarization in high-fat diet-fed mice
    Kang, J.W.; Shin, J.K.; Koh, E.J.; Ryu, H.; Kim, H.J.; Lee, S.M.
  • The impact of dietary feta cheese and butter on serum lipid profile and fatty acid composition in rat
    Khodadadi, I.H.A.; Karami, M.
  • Gut microbiota-derived short-chain fatty acids, T cells, and inflammation
    Kim, C.H.; Park, J.; Kim, M.
  • From dietary fiber to host physiology: Short-Chain fatty acids as key bacterial metabolites
    Koh, A.; De Vadder, F.; Kovatcheva-Datchary, P.; Backhed, F.
  • Changes of glycogen content in liver, skeletal muscle, and heart from fasted rats
    Kokubun, E.; Hirabara, S.M.; Fiamoncini, J.; Curi, R.; Haebisch, H.
  • Blood glucose area under the curve. Methodological aspects
    Le Floch, J.P.; Escuyer, P.; Baudin, E.; Baudon, D.; Perlemuter, L.
  • Hypoglycemic effect of opuntia ficus-indica var. saboten is due to enhanced peripheral glucose uptake through activation of AMPK/p38 MAPK pathway
    Leem, K.H.; Kim, M.G.; Hahm, Y.T.; Kim, H.K.
  • [hypoglycemic effect of extracts of cactus pear fruit polysaccharide in rats]
    Liu, H.G.; Liang, Q.Y.; Meng, H.L.; Huang, H.X.
  • Inhibition of acetyl-CoA carboxylase by cystamine may mediate the hypotriglyceridemic activity of pantethine
    Mccarty, M.F.
  • The new total Western diet for rodents does not induce an overweight phenotype or alter parameters of metabolic syndrome in mice
    Monsanto, S.P.; Hintze, K.J.; Ward, R.E.; Larson, D.P.; Lefevre, M.; Benninghoff, A.D.
  • Opuntia ficus indica (nopal) attenuates hepatic steatosis and oxidative stress in obese zucker (fa/fa) rats
    Moran-Ramos, S.; Avila-Nava, A.; Tovar, A.R.; Pedraza-Chaverri, J.; Lopez-Romero, P.; Torres, N.
  • Impacts of maternal diet and exercise on offspring behavior and body weights
    Moser, V.C.; Mcdaniel, K.L.; Woolard, E.A.; Phillips, P.M.; Franklin, J.N.; Gordon, C.J.
  • Effect of a diet enriched with fresh coconut saturated fats on plasma lipids and erythrocyte fatty acid composition in normal adults
    Nagashree, R.S.; Manjunath, N.K.; Indu, M.; Ramesh, M.; Venugopal, V.; Sreedhar, P.; Pavithra, N.; Nagendra, H.R.
  • Murinometric evaluations and feed efficiency in rats from reduced litter during lactation and submitted or not to swimming exercise
    Nery, C.D.S.; Pinheiro, I.L.; Muniz, G.; De, S.; De Vasconcelos, D.A.A.; De França, S.P.; Do Nascimento, E.
  • Functional and hypoglycemic properties of nopal cladodes (O. ficus-indica) at different maturity stages using in vitro and in vivo tests
    Nunez-Lopez, M.A.; Paredes-Lopez, O.; Reynoso-Camacho, R.
  • Western-style fast food intake and cardiometabolic risk in an Eastern country
    Odegaard, A.O.; Koh, W.P.; Yuan, J.M.; Gross, M.D.; Pereira, M.A.
  • Prickly pear induces upregulation of liver LDL binding in familial heterozygous hypercholesterolemia
    Palumbo, B.; Efthimiou, Y.; Stamatopoulos, J.; Oguogho, A.; Budinsky, A.; Palumbo, R.; Sinzinger, H.
  • AIN-93 purified diets for laboratory rodents: final report of the american institute of nutrition ad hoc writing committee on the reformulation of the AIN-76A rodent diet
    Reeves, P.G.; Nielsen, F.H.; Fahey, G.C.
  • Isorhamnetin derivatives and piscidic acid for hypercholesterolemia: cholesterol permeability, HMG-CoA reductase inhibition, and docking studies
    Ressaissi, A.; Attia, N.; Fale, P.L.; Pacheco, R.; Victor, B.L.; Machuqueiro, M.; Serralheiro, M.L.M.
  • The effect of isorhamnetin glycosides extracted from opuntia ficus-indica in a mouse model of diet induced obesity
    Rodriguez-Rodriguez, C.; Torres, N.; Gutierrez-Uribe, J.A.; Noriega, L.G.; Torre-Villalvazo, I.; Leal-Diaz, A.M.; Antunes-Ricardo, M.; Marquez-Mota, C.; Ordaz, G.; Chavez-Santoscoy, R.A.; Serna-Saldivar, S.O.; Tovar, A.R.
  • Nopal (Opuntia ficus indica) protects from metabolic endotoxemia by modifying gut microbiota in obese rats fed high fat/sucrose diet
    Sanchez-Tapia, M.; Aguilar-Lopez, M.; Perez-Cruz, C.; Pichardo-Ontiveros, E.; Wang, M.; Donovan, S.M.; Tovar, A.R.; Torres, N.
  • Analysis of time-dependent adaptations in whole-body energy balance in obesity induced by high-fat diet in rats
    So, M.; Gaidhu, M.P.; Maghdoori, B.; Ceddia, R.B.
  • Dietary fibre and the risk of colorectal cancer: a case- control study
    Song, Y.; Liu, M.; Yang, F.G.; Cui, L.H.; Lu, X.Y.; Chen, C.
  • Soluble fiber with high water-binding capacity, swelling capacity, and fermentability reduces food intake by promoting satiety rather than satiation in rats
    Tan, C.; Wei, H.; Zhao, X.; Xu, C.; Zhou, Y.; Peng, J.
  • Effects of margarine and butter on lipid profile and serum fatty acid composition in rats
    Vahidinia, H.
  • The effects of a modified high-carbohydrate high-fat diet on metabolic syndrome parameters in male rats
    Wong, S.K.; Chin, K.Y.; Suhaimi, F.H.; Ahmad, F.; Ima-Nirwana, S.
  • Butyrate induces apoptosis by activating PDC and inhibiting complex I through SIRT3 inactivation
    Xu, S.; Liu, C.X.; Xu, W.; Huang, L.; Zhao, J.Y.; Zhao, S.M.