New CMOS potentiostat as ASIC for several electrochemical microsensors construction

New CMOS potentiostat as ASIC for several electrochemical microsensors construction Purpose – The purpose of this paper is to design and create a potentiostat that can be integrated and encapsulated within a microelectrode as a low‐cost electrochemical sensor. Recently, microsystems on sensors or lab on a chip using electrochemical detection of substances matters are pushing forward into the area of analysis. For providing electrochemical analysis, the microsystem has to be equipped with an integrated potentiostat. Design/methodology/approach – The integrated potentiostat with four current ranges (from 1 μ A to 1 mA) was designed in the CADENCE software environment using the AMIS CMOS 0.7 μ m technology and fabricated under the Europractice program. Memory cells of 48 bytes are implemented with the potentiostat using VERILOG. Findings – The characteristics of integrated potentiostat are strictly linear; the measured results confirm the simulated values. The potentiostat measurements error is about 1.5 percent and very low offsets are reached by the offset‐zeroing circuitry. Research limitations/implications – The detection limit of the current at the lowest range with respect to S / N ratio is about 10 nA. Practical implications – The integrated potentiostat is embedded on a screen‐printed sensor and its characteristics are successfully verified. Lower range of 100 nA can be implemented on a new microchip as well as rail‐to‐rail output circuitry would increase the voltage dynamic range. Originality/value – The integrated potentiostat with very good parameters is designed for a wide spectrum of electrochemical applications such as lab on a chip, embedded electrochemical systems, etc. The integrated system enables storing of information about the system measured, for instance, calibration and fabrication data of the electrochemical sensor. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Microelectronics International Emerald Publishing

New CMOS potentiostat as ASIC for several electrochemical microsensors construction

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Publisher
Emerald Publishing
Copyright
Copyright © 2010 Emerald Group Publishing Limited. All rights reserved.
ISSN
1356-5362
DOI
10.1108/13565361011009450
Publisher site
See Article on Publisher Site

Abstract

Purpose – The purpose of this paper is to design and create a potentiostat that can be integrated and encapsulated within a microelectrode as a low‐cost electrochemical sensor. Recently, microsystems on sensors or lab on a chip using electrochemical detection of substances matters are pushing forward into the area of analysis. For providing electrochemical analysis, the microsystem has to be equipped with an integrated potentiostat. Design/methodology/approach – The integrated potentiostat with four current ranges (from 1 μ A to 1 mA) was designed in the CADENCE software environment using the AMIS CMOS 0.7 μ m technology and fabricated under the Europractice program. Memory cells of 48 bytes are implemented with the potentiostat using VERILOG. Findings – The characteristics of integrated potentiostat are strictly linear; the measured results confirm the simulated values. The potentiostat measurements error is about 1.5 percent and very low offsets are reached by the offset‐zeroing circuitry. Research limitations/implications – The detection limit of the current at the lowest range with respect to S / N ratio is about 10 nA. Practical implications – The integrated potentiostat is embedded on a screen‐printed sensor and its characteristics are successfully verified. Lower range of 100 nA can be implemented on a new microchip as well as rail‐to‐rail output circuitry would increase the voltage dynamic range. Originality/value – The integrated potentiostat with very good parameters is designed for a wide spectrum of electrochemical applications such as lab on a chip, embedded electrochemical systems, etc. The integrated system enables storing of information about the system measured, for instance, calibration and fabrication data of the electrochemical sensor.

Journal

Microelectronics InternationalEmerald Publishing

Published: Jan 26, 2010

Keywords: Electrochemical devices; Sensors; Integrated circuits

References

  • Fast and simultaneous detection of heavy metals using a simple and reliable microchip‐electrochemistry route: an alternative approach to food analysis
    Chailapakul, O.; Korsrisakul, S.; Siangproh, W.; Grudpan, K.
  • Label‐free voltammetric detection of single‐nucleotide mismatches recognized by the protein MutS
    Masarik, M.; Cahova, K.; Kizek, R.; Palecek, E.; Fojta, M.
  • Detection of Cd, Pb, and Cu in non‐pretreated natural waters and urine with thiol functionalized mesoporous silica and Nafion composite electrodes
    Yantasee, W.; Charnhattakorn, B.; Fryxell, G.E.; Lin, Y.H.; Timchalk, C.; Addleman, R.S.

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