Effects of calcium supplementation on iron bioavailability from spirulina

Effects of calcium supplementation on iron bioavailability from spirulina Purpose – The purpose of this study is to determine the effect of calcium supplementation on the iron bioavailability from spirulina (SP) and ferrous sulphate (FE) as reference in iron deficient rats. Design/methodology/approach – Sixty‐four weanling male Sprague‐Dawley rats were first depleted of iron by giving low iron diet for a period of 28 days. The anaemic rats were repleted with iron sources from SP, spirulina+CaCO3 (SPC), FE, FeSO4+CaCO3 (FEC), normal diet (ND), normal diet+CaCO3 (NDC) for 21 days. Iron level of FE supplementation was twice the level of that in SP supplementation. Haematological variables were measured on the last day of preexperimental period and at the end of the repletion period. Findings – Paired samples t ‐test at P <0.05 showed that haemoglobin (Hb) and haematocrit (Ht) was increased in all the groups. The diet with added calcium did not significantly inhibit haemoglobin repletion after 21 days in SP and FE. The haemoglobin repletion efficiency (HRE) was significantly higher in rats fed with SP compared to FE ( P >0.05). The presence of calcium did not significantly reduce the HRE of these groups. Originality/value – This paper provides information on effects of additional calcium on iron bioavailability from SP as the intake of dietary supplementation is increasing worldwide. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Nutrition & Food Science Emerald Publishing

Effects of calcium supplementation on iron bioavailability from spirulina

9 pages
Read Article

Loading next page...
 
/lp/emerald-publishing/effects-of-calcium-supplementation-on-iron-bioavailability-from-S90Bxb5hk7
Publisher
Emerald Publishing
Copyright
Copyright © 2006 Emerald Group Publishing Limited. All rights reserved.
ISSN
0034-6659
DOI
10.1108/00346650610712243
Publisher site
See Article on Publisher Site

Abstract

Purpose – The purpose of this study is to determine the effect of calcium supplementation on the iron bioavailability from spirulina (SP) and ferrous sulphate (FE) as reference in iron deficient rats. Design/methodology/approach – Sixty‐four weanling male Sprague‐Dawley rats were first depleted of iron by giving low iron diet for a period of 28 days. The anaemic rats were repleted with iron sources from SP, spirulina+CaCO3 (SPC), FE, FeSO4+CaCO3 (FEC), normal diet (ND), normal diet+CaCO3 (NDC) for 21 days. Iron level of FE supplementation was twice the level of that in SP supplementation. Haematological variables were measured on the last day of preexperimental period and at the end of the repletion period. Findings – Paired samples t ‐test at P <0.05 showed that haemoglobin (Hb) and haematocrit (Ht) was increased in all the groups. The diet with added calcium did not significantly inhibit haemoglobin repletion after 21 days in SP and FE. The haemoglobin repletion efficiency (HRE) was significantly higher in rats fed with SP compared to FE ( P >0.05). The presence of calcium did not significantly reduce the HRE of these groups. Originality/value – This paper provides information on effects of additional calcium on iron bioavailability from SP as the intake of dietary supplementation is increasing worldwide.

Journal

Nutrition & Food Science – Emerald Publishing

Published: Nov 1, 2006

Keywords: Diet; Nutrition

References

  • Comparative haematiolgy during deficiencies of iron and vitamin A in rat
    Amine, E.K.; Corey, J.; Hegsted, D.M.; Hayes, K.C.
  • Comparison of oral and intraperitoneal iron supplementation in anaemic rats: a re‐evaluation of the mucosal block theory of iron absorption
    Benito, P.; House, W.; Miller, D.
  • Nutritional iron requirements and food iron absorption
    Bothwell, T.H.; Baynes, R.D.; MacFarlane, B.J.; MacPhail, A.P.
    Bookmark
  • Calcium supplementation: effect on iron absorption
    Cook, J.D.; Dassenko, S.A.; Whittaker, P.
  • Nutritional value of alga spirulina
    Dillon, J.C.; Phuc, A.P.; Dubacq, J.P.
  • Duration of the inhibitory effect of calicum on non‐haem iron absorption in man
    Gleerup, A.; Rossander‐Hulten, L.; Hallberg, L.
  • Relationship of components in wheat bran and spinach to iron bioavailability in anemic rat
    Gordon, D.T.; Chao, L.S.
  • The enhancement of nonheme iron bioavailability by beef protein in the rat
    Gordon, D.T.; Godber, J.S.
  • Calcium: effect of different amounts on nonheme‐ and heme‐iron absorption in humans
    Hallberg, L.; Brune, M.; Erlandsson, M.; Sandberg, A.S.; Rossander‐Hulten, L.
  • Availability of iron to rats from Spirulina , a blue‐green alga
    Johnson, P.E.; Shubert, L.E.
  • Iron status and growth of rats fed different dietary iron sources
    Kapoor, R.; Mehta, U.
  • Microalgae as food and supplement
    Kay, R.A.
  • Effect of dietary iron level on efficiency of converting food iron into hemoglobin by the anemic rat
    Mahoney, A.W.; Hendricks, D.G.
  • Assessment of dietary iron availability by rat Hb repletion assay
    Miller, J.
  • Milk consumption and bone mineral density in middle aged and elderly women
    Murphy, S.; Khaw, K.T.; May, H.; Compston, J.E.
  • Research directions in osteoporosis
    Peck, W.A.; Riggs, B.L.; Bell, N.H.; Wallace, R.B.; Johnston, C.C. Jr; Gordon, S.L.; Shulman, L.E.
  • Calcium carbonate depresses iron bioavailability in rats more than calcium sulfate or sodium carbonate
    Prather, T.A.; Miller, D.D.
  • Iron availability from iron‐fortified spirulina by an in vitro digestion/Caco‐2 cell culture model
    Puyfoulhoux, G.; Rouanet, J.M.; Besancon, P.; Baroux, B.; Baccou, J.C.; Caporiccio, B.
  • Iron Bioavailability from Amaranthus species: 2‐evaluation using haemoglobin repletion in anaemic rats
    Rangarajan, A.; Chenoweth, W.A.; Kelly, J.K.; Agee, K.M.
    Bookmark
  • True absorption and retention of supplemental iron is more efficient when iron is administered every three days rather than daily to iron‐normal and iron‐deficient rats
    Viteri, F.E.; Liu, X.; Tolomei, K.; Martin, A.
  • How calcium from calcium carbonate and milk benefit peptic ulcer patients
    Wang, X.
    Bookmark
  • Mechanism underlying the inhibitory effect of high calcium carbonate intake on iron bioavailability from ferrous sulphate in anaemic rats
    Wienk, K.J.; Marx, J.J.; Lemmens, A.G.; Brink, E.J.; Van Der Meer, R.; Beynen, A.C.
  • The effectiveness of various iron‐supplementation regimens in improving the Fe status of anaemic rats
    Wright, A.J.; Southon, S.

You’re reading a free preview. Subscribe to read the entire article.

Try 2 weeks free now

DeepDyve is your
personal research library

It’s your single place to instantly
discover and read the research
that matters to you.

Enjoy affordable access to
over 18 million articles from more than
15,000 peer-reviewed journals.

All for just $49/month

Explore the DeepDyve Library

or browse the journals available

Search

Query the DeepDyve database, plus search all of PubMed and Google Scholar seamlessly

Organize

Save any article or search result from DeepDyve, PubMed, and Google Scholar... all in one place.

Access

Get unlimited, online access to over 18 million full-text articles from more than 15,000 scientific journals.

Your journals are on DeepDyve

Read from thousands of the leading scholarly journals from SpringerNature, Elsevier, Wiley-Blackwell, Oxford University Press and more.

All the latest content is available, no embargo periods.

See the journals in your area

DeepDyve

Freelancer

DeepDyve

Pro

Price

FREE

$49/month
$360/year

Save searches from
Google Scholar,
PubMed

Create folders to
organize your research

Export folders, citations

Read DeepDyve articles

Abstract access only

Unlimited access to over
18 million full-text articles

Print

20 pages / month

PDF Discount

20% off

Sign up
for free
Start 14 day
Free Trial