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Anti‐proliferative effects of pandan leaves ( Pandanus amarylfolius ), kantan flower ( Etlingera elatior ) and turmeric leaves ( Curcuma longa )

Anti‐proliferative effects of pandan leaves ( Pandanus amarylfolius ), kantan flower ( Etlingera... Purpose – The purpose of this paper is to screen cytotoxic activities of commonly used culinary plants in Malaysia, Pandanus amaryllifolius (daun pandan), Curcuma longa (turmeric leaves) and Etlingera elatior (kantan flower) against selected cancer cell lines. Design/methodology/approach – Plant samples were extracted exhaustively with ethanol and concentrated under rotary evaporator. Cytotoxic evaluation was carried out with plant extracts (0‐100 μ g/ml) using 72‐h MTT assay. Findings – Exposure of plant extracts reduced cell viability of HepG2 (hepatocellular carcinoma), HT‐29 (colon carcinoma), MDA‐MB‐231 (non‐hormone‐dependent breast cancer), MCF‐7 (hormone‐dependent breast cancer) and HeLa (cervical cancer); 50 percent inhibitory values (IC 50 ) were obtained for MDA‐MB‐231, HepG2, HT‐29. Extracts within the concentrations of 10‐100 μ g/ml were found not to be effective against proliferation of MCF‐7 and HeLa. Originality/value – The paper shows how culinary plants – daun pandan, turmeric leaves and kantan flower displayed selective cytotoxic effects towards liver, colon and breast cancer in vitro . http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Nutrition & Food Science Emerald Publishing

Anti‐proliferative effects of pandan leaves ( Pandanus amarylfolius ), kantan flower ( Etlingera elatior ) and turmeric leaves ( Curcuma longa )

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Publisher
Emerald Publishing
Copyright
Copyright © 2011 Emerald Group Publishing Limited. All rights reserved.
ISSN
0034-6659
DOI
10.1108/00346651111151366
Publisher site
See Article on Publisher Site

Abstract

Purpose – The purpose of this paper is to screen cytotoxic activities of commonly used culinary plants in Malaysia, Pandanus amaryllifolius (daun pandan), Curcuma longa (turmeric leaves) and Etlingera elatior (kantan flower) against selected cancer cell lines. Design/methodology/approach – Plant samples were extracted exhaustively with ethanol and concentrated under rotary evaporator. Cytotoxic evaluation was carried out with plant extracts (0‐100 μ g/ml) using 72‐h MTT assay. Findings – Exposure of plant extracts reduced cell viability of HepG2 (hepatocellular carcinoma), HT‐29 (colon carcinoma), MDA‐MB‐231 (non‐hormone‐dependent breast cancer), MCF‐7 (hormone‐dependent breast cancer) and HeLa (cervical cancer); 50 percent inhibitory values (IC 50 ) were obtained for MDA‐MB‐231, HepG2, HT‐29. Extracts within the concentrations of 10‐100 μ g/ml were found not to be effective against proliferation of MCF‐7 and HeLa. Originality/value – The paper shows how culinary plants – daun pandan, turmeric leaves and kantan flower displayed selective cytotoxic effects towards liver, colon and breast cancer in vitro .

Journal

Nutrition & Food ScienceEmerald Publishing

Published: Jul 19, 2011

Keywords: Malaysia; Plants; Cytology; Cytotoxic effect; Pandanus amaryllifolius ; Curcuma longa ; Etlingera elatior ; MTT assay

References