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-culture environment, ZA still decreases the differentiation of osteoclasts. Furthermore, this effect can be combined with the reduction in osteoclast formation caused by mechanically stimulated osteocytes ...
formation without causing osteocyte death in mice Arch Oral Biol 2009 ; 54 : 851 – 856 . Google Scholar Crossref Search ADS PubMed WorldCat 34 Horie D , Takahashi M, Aoki K et al. Clodronate stimulates bone ...
were found without evident bone formation in the PBS group (Fig 4f) and the control group (Fig 4g). Download: PPT PowerPoint slide PNG larger image TIFF original image Fig 4. Typical micro-CT images ...
increase in periosteal bone formation . Short-term loading decreased the number of sclerostin-positive osteocytes in sham, whereas in control fibulas, ORX decreased and T increased the number of sclerostin ...
of the findings between i.v. and oral BPs, our results are presented in a stratified analysis by type of BP. It seems that zoledronic acid has the highest, most expeditious impact on bone to cause BONJ. For users ...
deficiency protected against glucocorticoid-induced bone loss but did not protect against a decrease in bone formation or an increase in osteoblast/ osteocyte apoptosis (90). The protection appeared due ...
of bone formation (88). PTH(1-34) treatment decreased Sost mRNA and sclerostin protein in UMR106 OS cells and in murine bone (89,90) an effect mediated by MEF2 transcription factors in a cAMP-dependent ...
and greatly diminished bone formation (Figure 1), so ideal treatment would prevent or diminish resorption and promote bone anabolism.Figure 1. Causes of glucocorticoid-induced bone loss. RANKL indicates receptor ...
by a resting phase.9,10 The processes of bone resorption and bone formation are tightly coupled.10 Conditions causing increased bone resorption (e.g., menopause) or decreased bone formation (e.g., older age) may ...
will be necessary to explain the mechanisms that lead to development of osteonecrosis by an agent that causes bone formation . Incidence and Risk Factors MRONJ was not seen clinically before use of antiresorptive ...
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