•Introducing an efficient viral delivery technique for optogenetics in NHP.•Convection-enhanced delivery (CED) of virus leads to high levels of expression.•Wide-spread optogenetic expression across cortical areas following thalamic CED.•Expression is limited to specific areas due to thalmo-cortico-thalamic projections.•Reliable light-evoked activity from single cells in cortex following thalamic CED.
Journal of Neuroscience Methods – Elsevier
Published: Jan 1, 2018
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