Visuo-spatial short-term recognition memory and learning after temporal lobe excisions, frontal lobe excisions or amygdalo-hippocampectomy in man

Visuo-spatial short-term recognition memory and learning after temporal lobe excisions, frontal... Three groups of neurosurgical patients with temporal lobe excisions, frontal lobe excisions or unilateral amygdalo-hippocampectomy were assessed on a computerized battery of tasks designed to investigate visuo-spatial short-term recognition memory and learning. A double dissociation is reported between deficits of pattern recognition memory and spatial recognition memory which were observed in the two posterior groups and frontal lobe patients, respectively. In addition, both the temporal lobe and amygdalo-hippocampectomy patients were also impaired on a delayed matching-to-sample paradigm whilst frontal lobe patients performed at an equivalent level to controls. Finally, whilst the impaired performance of the three groups was indistinguishable on a test of paired-associate learning, quite different patterns of deficit were observed on a test of spatial working memory. These results are discussed with reference to recent suggestions that visual recognition memory is mediated by a neural system which includes, as major components, the inferotemporal cortex, the medial temporal lobe structures and particular sectors of the frontal lobe, and are compared to previous findings from patients with idiopathic Parkinson's disease and dementia of the Alzheimer type. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Neuropsychologia Elsevier

Visuo-spatial short-term recognition memory and learning after temporal lobe excisions, frontal lobe excisions or amygdalo-hippocampectomy in man

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Publisher
Elsevier
Copyright
Copyright © 1995 Elsevier Ltd
ISSN
0028-3932
DOI
10.1016/0028-3932(94)00098-A
Publisher site
See Article on Publisher Site

Abstract

Three groups of neurosurgical patients with temporal lobe excisions, frontal lobe excisions or unilateral amygdalo-hippocampectomy were assessed on a computerized battery of tasks designed to investigate visuo-spatial short-term recognition memory and learning. A double dissociation is reported between deficits of pattern recognition memory and spatial recognition memory which were observed in the two posterior groups and frontal lobe patients, respectively. In addition, both the temporal lobe and amygdalo-hippocampectomy patients were also impaired on a delayed matching-to-sample paradigm whilst frontal lobe patients performed at an equivalent level to controls. Finally, whilst the impaired performance of the three groups was indistinguishable on a test of paired-associate learning, quite different patterns of deficit were observed on a test of spatial working memory. These results are discussed with reference to recent suggestions that visual recognition memory is mediated by a neural system which includes, as major components, the inferotemporal cortex, the medial temporal lobe structures and particular sectors of the frontal lobe, and are compared to previous findings from patients with idiopathic Parkinson's disease and dementia of the Alzheimer type.

Journal

NeuropsychologiaElsevier

Published: Jan 1, 1995

References

  • Effects of foveal prestriate and inferotemporal lesions on visual discrimination by rhesus monkeys
    Cowey, A.; Gross, C.G.
  • Inferotemporal-frontal disconnection: The uncinate fascicle and visual associative learning in monkeys
    Eacott, M.J.; Gaffan, D.
  • Mnemonic coding of visual space in the monkey's dorsolateral prefrontal cortex
    Funahashi, S.; Bruce, C.J.; Goldman-Rakic, P.S.
  • Visuospatial coding of primate prefrontal neurons revealed by oculomotor paradigms
    Funahashi, S.; Bruce, C.J.; Goldman-Rakic, P.S.
  • L-Dopa withdrawal in Parkinson's disease selectively impairs cognitive performance in tests sensitive to frontal lobe dysfunction
    Lange, K.W.; Robbins, T.W.; Marsden, C.D.; James, M.; Owen, A.M.; Paul, G.M.
  • Visual recognition and recall after right temporal-excision in man
    Milner, B.
  • Effects of small frontal lesions on delayed alternation in monkeys
    Mishkin, M.
  • Frontal lobes and memory
    Petrides, M.

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