Validation of salivary oxytocin and vasopressin as biomarkers in domestic dogs

Validation of salivary oxytocin and vasopressin as biomarkers in domestic dogs •We validated immunoassays for measuring oxytocin (OT) and vasopressin (AVP) in dog saliva.•OT and AVP were present in dog saliva and detectable by ELISA and HPLC–MS.•Assays yielded good parallelism and accuracy, both with and without extraction.•Dams exhibited an increase in both salivary and plasma OT when nursing their litters http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Journal of Neuroscience Methods Elsevier

Validation of salivary oxytocin and vasopressin as biomarkers in domestic dogs

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Publisher
Elsevier
Copyright
Copyright © 2017 Elsevier B.V.
ISSN
0165-0270
eISSN
1872-678X
D.O.I.
10.1016/j.jneumeth.2017.08.033
Publisher site
See Article on Publisher Site

Abstract

•We validated immunoassays for measuring oxytocin (OT) and vasopressin (AVP) in dog saliva.•OT and AVP were present in dog saliva and detectable by ELISA and HPLC–MS.•Assays yielded good parallelism and accuracy, both with and without extraction.•Dams exhibited an increase in both salivary and plasma OT when nursing their litters

Journal

Journal of Neuroscience MethodsElsevier

Published: Jan 1, 2018

References

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