Utility of C-Reactive Protein Measurement in Risk Stratification During Primary Cardiovascular Disease Prevention

Utility of C-Reactive Protein Measurement in Risk Stratification During Primary Cardiovascular... High-sensitivity C-reactive protein (hs-CRP) adds prognostic information beyond that provided by the Framingham risk score. The clinical utility of hs-CRP evaluation per guidelines was investigated by determining how it changed the cardiovascular risk stratification of 100 patients deemed at intermediate risk. Screening guidelines defined the cardiovascular risk due to hs-CRP as low (<1.0 mg/L), intermediate (1.0 to 3.0 mg/L), or high (>3.0 mg/L). After hs-CRP evaluation, risk was adjusted in 66% of the patients. Because hs-CRP evaluation significantly altered the cardiovascular risk strata of most intermediate-risk patients, it may therefore be a useful test during primary cardiovascular disease prevention. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png The American Journal of Cardiology Elsevier

Utility of C-Reactive Protein Measurement in Risk Stratification During Primary Cardiovascular Disease Prevention

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Publisher
Elsevier
Copyright
Copyright © 2005 Excerpta Medica Inc.
ISSN
0002-9149
D.O.I.
10.1016/j.amjcard.2005.01.089
Publisher site
See Article on Publisher Site

Abstract

High-sensitivity C-reactive protein (hs-CRP) adds prognostic information beyond that provided by the Framingham risk score. The clinical utility of hs-CRP evaluation per guidelines was investigated by determining how it changed the cardiovascular risk stratification of 100 patients deemed at intermediate risk. Screening guidelines defined the cardiovascular risk due to hs-CRP as low (<1.0 mg/L), intermediate (1.0 to 3.0 mg/L), or high (>3.0 mg/L). After hs-CRP evaluation, risk was adjusted in 66% of the patients. Because hs-CRP evaluation significantly altered the cardiovascular risk strata of most intermediate-risk patients, it may therefore be a useful test during primary cardiovascular disease prevention.

Journal

The American Journal of CardiologyElsevier

Published: Jun 1, 2005

References

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