Geriatric Nursing 39 (2018) 350–351 Contents lists available at ScienceDirect Geriatric Nursing journal homepage: www.gnjournal.com Pharmacy Column William Simonson, PharmD, BCGP, FASCP William Simonson, PharmD, BCGP, FASCP * Oregon State University, Corvallis, OR, USA Statin drugs are one of the most commonly used classes of medi- statins that substantially expanded the population eligible for statin cations, and one of the most controversial. The ﬁrst statin, lovastatin, therapy. They based their recommendations on an estimated el- was approved by the US Food and Drug Administration (FDA) in 1987. evated 10-year risk of atherosclerotic cardiovascular disease by Additional statins received FDA approval, mostly in the 1990’s. Statins basically identifying four high-risk groups: individuals who had now available as single agent products include atorvastatin (Lipitor), already experienced a cardiovascular event (stroke or heart attack), ﬂuvastatin (Lescol, Lescol XL), lovastatin (Mevacor, Altoprev), diabetics between the age of 40 and 69, persons with an elevated pravastatin (Pravachol), rosuvastatin (Crestor), simvastatin (Zocor, LDL, and older men. These guidelines are based on an estimation FloLipid) and pitavastatin (Livalo) and some statins are available in of an individual’s risk of experiencing a cardiovascular event in the combination products. Fifteen million Americans now take statin next ten years.
Geriatric Nursing – Elsevier
Published: May 1, 2018
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