Unveiling ribosomal structures: the final phases

Unveiling ribosomal structures: the final phases Unprecedented insights into the structure of the ribosome have been gained recently: X-ray crystallographic studies have yielded 5–9 Å resolution structures and cryo-electron microscopy has elucidated the structure of the Escherichia coli ribosome in different functional states. A 7.5 Å cryo-electron microscopy structure of the large subunit indicates that this technique is still in the race to determine the ribosome structure. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Current Opinion in Structural Biology Elsevier

Unveiling ribosomal structures: the final phases

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Publisher
Elsevier
Copyright
Copyright © 2000 Elsevier Science Ltd
ISSN
0959-440x
DOI
10.1016/S0959-440X(00)00077-4
Publisher site
See Article on Publisher Site

Abstract

Unprecedented insights into the structure of the ribosome have been gained recently: X-ray crystallographic studies have yielded 5–9 Å resolution structures and cryo-electron microscopy has elucidated the structure of the Escherichia coli ribosome in different functional states. A 7.5 Å cryo-electron microscopy structure of the large subunit indicates that this technique is still in the race to determine the ribosome structure.

Journal

Current Opinion in Structural BiologyElsevier

Published: Apr 1, 2000

References

  • Cryo-electron microscopy of vitrified specimens
    Dubochet, J.; Adrian, M.; Chang, J.J.; Homo, J.C.; Lepault, J.; McDowell, A.W.; Schultz, P.
  • Structural studies of the translational apparatus
    Agrawal, R.K.; Frank, J.
  • Ribosomal protein L9: a structure determination by the combined use of X-ray crystallography and NMR spectroscopy
    Hoffman, D.W.; Cameron, C.S.; Davies, C.; White, S.; Ramakrishnan, V.
  • The three-dimensional structure of the RNA-binding domain of ribosomal protein L2; a protein at the peptidyl transferase center of the ribosome
    Nakagawa, A.; Nakashima, T.; Taniguchi, M.; Hosaka, H.; Kimura, M.; Tanaka, I.

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