Journal of Colloid and Interface Science 461 (2016) 225–231 Contents lists available at ScienceDirect Journal of Colloid and Interface Science journal homepage: www.elsevier.com/locate/jcis Understanding the interactions between porphyrin-containing photosensitizers and polymer-coated nanoparticles in model biological environments a b a a c a Samir V. Jenkins , Avinash Srivatsan , Kimberly Y. Reynolds , Feng Gao , Yongbin Zhang , Colin D. Heyes , b a,⇑ Ravindra K. Pandey , Jingyi Chen Department of Chemistry and Biochemistry, University of Arkansas, Fayetteville, AR 72701, United States Photodynamic Therapy Center, Roswell Park Cancer Institute, Buffalo, NY 14263, United States NCTR/ORA Nanotechnology Core Facility, National Center for Toxicological Research, U.S. Food and Drug Administration, Jefferson, AR 72079, United States graphical a bstract article i nfo abstract Article history: Non-covalent incorporation of hydrophobic drugs into polymeric systems is a commonly-used strategy Received 22 July 2015 for drug delivery because non-covalent interactions minimize modiﬁcation of the drug molecules whose Revised 14 September 2015 efﬁcacy is retained upon release. The behaviors of the drug–polymer delivery system in the biological Accepted 14 September 2015 environments it encounters will affect the efﬁcacy of treatment. In this report, we have investigated Available online 15 September 2015 the interaction between
Journal of Colloid and Interface Science – Elsevier
Published: Jan 1, 2016
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