Understanding regulation in substrate dependent modulation of growth and production of alcohols in Clostridium sporogenes NCIM 2918 through metabolic network reconstruction and flux balance analysis

Understanding regulation in substrate dependent modulation of growth and production of alcohols... •First instance of metabolic network reconstruction and FBA for C. sporogenes.•FBA was performed for C. sporogenes NCIM 2918 on glucose, glycerol & their blend.•Glucose & glucose-glycerol blend favored improved growth & butyric acid production.•Glycerol fermentation was marked by reduced growth & predominant ethanol synthesis.•Distinctive feature of glucose fermentation was lack of butyric acid reutilization. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Bioresource Technology Elsevier

Understanding regulation in substrate dependent modulation of growth and production of alcohols in Clostridium sporogenes NCIM 2918 through metabolic network reconstruction and flux balance analysis

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Publisher
Elsevier
Copyright
Copyright © 2017 Elsevier Ltd
ISSN
0960-8524
D.O.I.
10.1016/j.biortech.2017.10.080
Publisher site
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Abstract

•First instance of metabolic network reconstruction and FBA for C. sporogenes.•FBA was performed for C. sporogenes NCIM 2918 on glucose, glycerol & their blend.•Glucose & glucose-glycerol blend favored improved growth & butyric acid production.•Glycerol fermentation was marked by reduced growth & predominant ethanol synthesis.•Distinctive feature of glucose fermentation was lack of butyric acid reutilization.

Journal

Bioresource TechnologyElsevier

Published: Feb 1, 2018

References

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