Type IV transporters of pathogenic bacteria

Type IV transporters of pathogenic bacteria Type IV transporters are produced by several bacterial pathogens such as Agrobacterium tumefaciens , Bordetella pertussis , Brucella spp., Bartonella henselae , Helicobacter pylori and Legionella pneumophila . These transporters are critical for the pathogenic process in that they export important virulence factors across the membranes of the bacteria. Although the virulence factors that are exported by these transporters can be either nucleic acid or protein, the general mechanism of transport appears to be similar for members of this family. Recent findings have shed light on the architecture of type IV transporters and the roles that these transporters play in pathogenesis. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Current Opinion in Microbiology Elsevier

Type IV transporters of pathogenic bacteria

Current Opinion in Microbiology, Volume 6 (1) – Feb 1, 2003

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Publisher
Elsevier
Copyright
Copyright © 2003 Elsevier Science Ltd
ISSN
1369-5274
DOI
10.1016/S1369-5274(02)00006-1
Publisher site
See Article on Publisher Site

Abstract

Type IV transporters are produced by several bacterial pathogens such as Agrobacterium tumefaciens , Bordetella pertussis , Brucella spp., Bartonella henselae , Helicobacter pylori and Legionella pneumophila . These transporters are critical for the pathogenic process in that they export important virulence factors across the membranes of the bacteria. Although the virulence factors that are exported by these transporters can be either nucleic acid or protein, the general mechanism of transport appears to be similar for members of this family. Recent findings have shed light on the architecture of type IV transporters and the roles that these transporters play in pathogenesis.

Journal

Current Opinion in MicrobiologyElsevier

Published: Feb 1, 2003

References

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