Treatment of experimental necrotizing enterocolitis with stem cell-derived exosomes

Treatment of experimental necrotizing enterocolitis with stem cell-derived exosomes PurposeNecrotizing enterocolitis (NEC) remains a devastating disease in premature infants. We previously showed that four stem cell (SC) types equivalently improve experimental NEC. Exosomes are intercellular nanovesicles containing RNA, miRNA, DNA, and protein. Because SC therapy faces challenges, our aim was to determine if the beneficial effects of SC are achievable with cell-free exosomes. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Journal of Pediatric Surgery Elsevier

Treatment of experimental necrotizing enterocolitis with stem cell-derived exosomes

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Publisher
Elsevier
Copyright
Copyright © 2018 Elsevier Inc.
ISSN
0022-3468
D.O.I.
10.1016/j.jpedsurg.2018.02.086
Publisher site
See Article on Publisher Site

Abstract

PurposeNecrotizing enterocolitis (NEC) remains a devastating disease in premature infants. We previously showed that four stem cell (SC) types equivalently improve experimental NEC. Exosomes are intercellular nanovesicles containing RNA, miRNA, DNA, and protein. Because SC therapy faces challenges, our aim was to determine if the beneficial effects of SC are achievable with cell-free exosomes.

Journal

Journal of Pediatric SurgeryElsevier

Published: Jun 1, 2018

References

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