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Dendritic cells (DCs) dictate the outcomes of tissue-specific immune responses. In the context of autoimmune diseases , DCs instruct T cells to respond to antigens (Ags), including self-Ags, leading ...
of differentiation order to manipulate this duality, DC have been generated ex DEC Dendritic and epithelial cells vivo with a tolerogenic or immunogenic profile since several MHC Major histocompatibility complex years ...
Immune thrombocytopenia (ITP) is an autoimmune disease in which platelets are destroyed by special antiplatelet autoantibodies produced by B cells . Dendritic cells (DCs) are professional antigen ...
Induced tolerogenic dendritic cells are a powerful immunotherapy for autoimmune disease that have shown promise in laboratory models of disease and early clinical trials. In contrast to conventional ...
Springer-Verlag Berlin Heidelberg 2017 Dendritic cells (DCs) play a central role in the control well as their modulation by disease -modifying therapies of the adaptive immune response. DCs drive the differ ...
REVIEW URRENT PINION Catharina C. Gross and Heinz Wiendl Purpose of review Autoimmune diseases are the result of an imbalanced immune regulatory network. Tolerogenic dendritic cells (tolDCs) are key ...
, rheumatoid arthritis, Crohn’s disease and multiple sclerosis. Dendritic cells (DCs) are the most efficient antigen-presenting cells and can naturally acquire tolerogenic properties through a variety ...
and other autoimmune diseases . cells Review Current Paradigms of Tolerogenic Dendritic Cells and Clinical Implications for Systemic Lupus Erythematosus 1 , 2 3 3 , 4 , Patcharee Ritprajak , Chamraj ...
Tolerogenic dendritic cells (tolDC) regulate the immune response, several clinical trials focused on autoimmune diseases use tolDC to promote immune tolerance response and Treg activation. Here we ...
therapies are aimed at exploiting their tolerogenic capacity. R E V I E W S Dendritic cells as targets for therapy in rheumatoid arthritis Shaukat Khan, Jeffrey D. Greenberg and Nina Bhardwaj Abstract ...
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