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The Use of Platelet-Rich Plasma in Sports Medicine—the International Olympic Committee Opinion

Acute and chronic musculoskeletal injuries in sports are common and problematic for both athletes and clinicians. A significant proportion of these injuries remain difficult to treat, and many athletes suffer from decreased performance and long-standing pain and discomfort. 1 </P>In 2008, the International Olympic Committee (IOC) published a consensus document on the importance of molecular mechanisms in connective tissue and skeletal muscle injury and healing. 2 This document predicted an increase in the use of autologous growth factors, as has indeed happened following that publication.</P>Platelet-rich plasma (PRP, also referred to as platelet rich in growth factors, platelet-rich fibrin matrix, platelet-rich fibrin, fibrin sealant, platelet concentrate) is now being widely used to treat musculoskeletal injuries in sports and draws widespread media attention, despite the absence of robust clinical studies to support its use. 3 Of the few studies published on the effectiveness of PRP in clinical settings, only very few are of sufficient methodological quality that would enable evidence-based decision making. On January 1, 2011, the World Anti-Doping Agency eased the restrictions on PRP, citing that there was no evidence that the procedure enhanced performance.</P>PRP and its variant forms were originally used in clinical practice as an adjunct to http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Operative Techniques in Orthopaedics Elsevier
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