The time course of adaptation in macaque retinal ganglion cells

The time course of adaptation in macaque retinal ganglion cells The time course of adaptation of cells of the parvocellular (PC) and magnocellular (MC) pathways has been characterized following changes in retinal illuminance or chromaticity. Adaptation state was cycled between high and low luminance levels or between backgrounds with wavelengths metameric to 630 and 570 um. Cell responsivity was probed with brief bursts of luminance or chromatic modulation. After a change in luminance, adaptation of both MC-cells (tested with a luminance probe) and red-green PC-cells (tested with a chromatic probe) was relatively rapid and largely complete within 100 msec or less. After a change in chromaticity, recovery of responsivity in red-green PC-cells was dependent on cell type. Recovery of responsivity with backgrounds elevating maintained firing was complete within a few seconds, but with backgrounds suppressing cell firing, recovery took many tens of seconds. This very slow time course may be due to a threshold effect. In experiments with backgrounds which selectively adapted one cone type, use of cone-isolating probes indicated that the time course of PC-cell chromatic adaptation may be determined at a site after the subtraction of cone signals. Recovery of responsivity of MC-cells was also prolonged over several seconds following a chromatic change. Our data suggest that adaptation in macaque ganglion cells depends on mechanisms both before and after the site of cone interaction, and that these mechanisms may differ in time course between MC- and PC-cells. The results indicate that it may be important in psychophysical adaptation experiments to consider the presence of multiple postreceptoral mechanisms with different adaptation characteristics. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Vision Research Elsevier

The time course of adaptation in macaque retinal ganglion cells

Vision Research, Volume 36 (7) – Apr 1, 1996

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Publisher
Elsevier
Copyright
Copyright © 1996 Elsevier Science Ltd. All rights reserved
ISSN
0042-6989
eISSN
1878-5646
D.O.I.
10.1016/0042-6989(95)00332-0
Publisher site
See Article on Publisher Site

Abstract

The time course of adaptation of cells of the parvocellular (PC) and magnocellular (MC) pathways has been characterized following changes in retinal illuminance or chromaticity. Adaptation state was cycled between high and low luminance levels or between backgrounds with wavelengths metameric to 630 and 570 um. Cell responsivity was probed with brief bursts of luminance or chromatic modulation. After a change in luminance, adaptation of both MC-cells (tested with a luminance probe) and red-green PC-cells (tested with a chromatic probe) was relatively rapid and largely complete within 100 msec or less. After a change in chromaticity, recovery of responsivity in red-green PC-cells was dependent on cell type. Recovery of responsivity with backgrounds elevating maintained firing was complete within a few seconds, but with backgrounds suppressing cell firing, recovery took many tens of seconds. This very slow time course may be due to a threshold effect. In experiments with backgrounds which selectively adapted one cone type, use of cone-isolating probes indicated that the time course of PC-cell chromatic adaptation may be determined at a site after the subtraction of cone signals. Recovery of responsivity of MC-cells was also prolonged over several seconds following a chromatic change. Our data suggest that adaptation in macaque ganglion cells depends on mechanisms both before and after the site of cone interaction, and that these mechanisms may differ in time course between MC- and PC-cells. The results indicate that it may be important in psychophysical adaptation experiments to consider the presence of multiple postreceptoral mechanisms with different adaptation characteristics.

Journal

Vision ResearchElsevier

Published: Apr 1, 1996

References

  • Chromatic difference steps of moderate size measured along theoretically critical axes
    Boynton, R.M.; Kambe, N.
  • Adaptation and dynamics of cat retinal ganglion cells
    Enroth-Cugell, C.; Shapley, R.M.
  • Sensitivity of macaque retinal ganglion cells to chromatic and luminance flicker
    Lee, B.B.; Martin, P.R.; Valberg, A.
  • Visual transduction in cones of the monkey Macaca fascicularis
    Schnapf, J.L.; Nunn, B.J.; Meister, M.; Baylor, D.A.
  • Responses of macaque ganglion cells to the relative phase of heterochromatically modulated lights
    Smith, V.C.; Lee, B.B.; Pokorny, J.; Martin, P.R.; Valberg, A.
  • Light adaptation in cells of macaque lateral geniculate nucleus and its relation to human light adaptation
    Virsu, V.; Lee, B.B.

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