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reported within the L4 region that allows for the early expression of L4 -22K and L4 -33K proteins important for the splicing of other late genes [46,47]. The MLTU encodes for primarily structural capsid ...
while leader L2 is less structured and leader L4 does not contain any stable secondary structure (not shown). Previously, it was established that transcripts with leaders 1, 2 and 4 are efficiently ...
. After primary lysis (7–10 days), crude adenovirus lysates were subject to freeze/thaw and further propagated in a confluent T25 flask of HEK293 cells to create a secondary lysate. For purification, six ...
and structural homology within their conserved ‘helicase’ core, their flanking N- and C-terminal domains are highly divergent and are thought to provide specificity of function through interaction with specific ...
contribution after the discovery of exons and introns in the adenovirus hexon gene in 1977 ( 2 ). Alternative splicing is now considered one of the main mechanisms responsible for increasing the diversity ...
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