•The octapeptide NAP exerts its beneficial effects not only in the central nervous system, but also in the intestinal tract.•For the first time, we here show that intraperitoneal application of NAP treatment alleviates acute murine colitis.•NAP treatment also reduces extra-intestinal collateral damages of induced colitis as shown for the kidneys.•NAP might open novel treatment options of intestinal inflammatory diseases in humans.
Peptides – Elsevier
Published: Mar 1, 2018
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